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Evidence for alternative quaternary structure in a bacterial Type III secretion system chaperone
(BioMed Central, 2010-07-15)
Background: Type III secretion systems are a common virulence mechanism in many Gram-negative bacterial pathogens. These systems use a nanomachine resembling a molecular needle and syringe to provide an energized conduit ...
Genes related to mitochondrial functions are differentially expressed in phosphine-resistant and -susceptible Tribolium castaneum
(BioMed Central, 2015-11-18)
Background: Phosphine is a valuable fumigant to control pest populations in stored grains and grain products. However, recent studies indicate a substantial increase in phosphine resistance in stored product pests worldwide.
Functional cloning of Bacillus anthracis dihydrofolate reductase and confirmation of natural resistance to trimethoprim
(American Society for Microbiology, 2004-12)
Bacillus anthracis is reported to be naturally resistant to trimethoprim (TMP), a drug that inhibits dihydrofolate reductase (DHFR), a key enzyme in the folate pathway. A microdilution broth assay established that the MIC ...