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Role of the Mycobacterium tuberculosis ESX-4 secretion system in heme iron utilization and pore formation by PPE proteins
(American Society for Microbiology, 2023-02-07)
Mycobacterium tuberculosis (Mtb) is transmitted through aerosols and primarily colonizes within the lung. The World Health Organization estimates that Mtb kills ~1.4 million people every year. A key aspect that makes Mtb ...
Exogenously scavenged and endogenously synthesized heme are differentially utilized by Mycobacterium tuberculosis
(American Society for Microbiology, 2022-10-26)
Heme is both an essential cofactor and an abundant source of nutritional iron for the human pathogen Mycobacterium tuberculosis. While heme is required for M. tuberculosis survival and virulence, it is also potentially ...
Invasive plants as foci of mosquito-borne pathogens: Red cedar in the southern Great Plains of the USA
(Springer Science and Business Media LLC, 2021-10-05)
West Nile virus (WNV) is the most significant mosquito-borne disease affecting humans in the United States. Eastern redcedar (ERC) is a native encroaching plant in the southern Great Plains that greatly alters abiotic ...
Recombinase polymerase amplification (RPA) with lateral flow detection for three Anaplasma species of importance to livestock health
(Springer Science and Business Media LLC, 2021)
Anaplasma marginale, A. ovis, and A. phagocytophilum are the causative agents of bovine anaplasmosis, ovine anaplasmosis, and granulocytic anaplasmosis, respectively. The gold standard for diagnosis of post-acute and ...
Mosquito-borne parasites in the Great Plains: Searching for vectors of nematodes and avian malaria parasites
(Elsevier BV, 2021)
Vector-borne diseases in the United States have recently increased as a result of the changing nature of vectors, hosts, reservoirs, parasite/pathogens, and the ecological and environmental conditions. While most focus has ...
Seroprevalence of Toxoplasma gondii infection among pregnant women in Windhoek, Namibia, in 2016
(AOSIS, 2020-05-13)
Background: When a pregnant woman contracts Toxoplasma gondii (T. gondii) infection during pregnancy, it may be vertically transmitted to the foetus. Information on the incidence of congenital toxoplasmosis (CT) in developing ...