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Single-fiber reflectance spectroscopy of isotropic-scattering medium: An analytic perspective to the ratio-of-remission in steady-state measurements
(MDPI, 2014-12-16)
Recent focused Monte Carlo and experimental studies on steady-state single-fiber reflectance spectroscopy (SfRS) from a biologically relevant scattering medium have revealed that, as the dimensionless reduced scattering ...
Diffuse optical tomography to monitor the photocoagulation front during interstitial photothermal therapy: Numerical simulations and measurements in tissue-simulating phantoms
(De Gruyter, 2014-08-06)
Near-infrared interstitial photothermal therapy (PTT) is currently undergoing clinical trials as an alternative to watchful waiting or radical treatments in patients with low/intermediate-risk focal prostate cancer. ...
The utility of direct-current as compared to frequency domain measurements in spectrally-constrained diffuse optical tomography toward cancer imaging
(SAGE Publications, 2011-10-01)
This work investigates, by means of analytical and simulation studies, the performance of spectrally-constrained image reconstruction in Continuous-Wave or Direct-Current (DC) and Frequency Domain (FD) near-infrared optical ...
On the geometry dependence of differential pathlength factor for near-infrared spectroscopy. I. Steady-state with homogeneous medium
(SPIE, the international society for optics and photonics, 2015-10-14)
This work analytically examines some dependences of the differential pathlength factor (DPF) for steady-state photon diffusion in a homogeneous medium on the shape, dimension, and absorption and reduced scattering coefficients ...
Toward transduodenal diffuse optical tomography of proximal pancreas
(Optica Publishing Group, 2013-10-10)
We demonstrate the feasibility of diffuse optical tomography (DOT) of the proximal pancreas by using optical applicator channels deployed longitudinally along the exterior surface of a duodenoscope. As the duodenum that ...
A low-cost needle-based single-fiber reflectance spectroscopy method to probe scattering changes associated with mineralization in intervertebral discs in chondrodystrophoid canine species - A pilot study
(De Gruyter, 2012-05-01)
Background and objectives: Intervertebral disc herniation is a common disease in chondrodystrophic dogs, and a similar neurologic condition also occurs in humans. Percutaneous laser disc ablation (PLDA) is a minimally ...
Transrectal ultrasound-integrated spectral optical tomography of hypoxic progression of a regressing tumor in a canine prostate
(SAGE Publications, 2011-12-01)
The objective of this study was to evaluate if transrectal optical tomography implemented at three wavelength bands for spectral detection could monitor changes of the hemoglobin oxygen saturation (SₜO₂) in addition to ...
Freehand diffuse optical spectroscopy imaging for intraoperative identification of major venous and arterial vessels underlying peritoneal fat: An in vivo demonstration in a pig model
(SPIE, the international society for optics and photonics, 2017-10-30)
Inadvertent injury to important anatomic structures is a significant risk in minimally invasive surgery (MIS) that potentially requires conversion to an open procedure, which results in increased morbidity and mortality. ...
In vivo assessment of diet-induced rat hepatic steatosis development by percutaneous single-fiber spectroscopy detects scattering spectral changes due to fatty infiltration
(SPIE, the international society for optics and photonics, 2015-11-05)
This study explores percutaneous single-fiber spectroscopy (SfS) of rat livers undergoing fatty infiltration. Eight test rats were fed a methionine-choline-deficient (MCD) diet, and four control rats were fed a normal diet. ...