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Exogenously scavenged and endogenously synthesized heme are differentially utilized by Mycobacterium tuberculosis
(American Society for Microbiology, 2022-10-26)
Heme is both an essential cofactor and an abundant source of nutritional iron for the human pathogen Mycobacterium tuberculosis. While heme is required for M. tuberculosis survival and virulence, it is also potentially ...
Age-specific mortality patterns in Central Mozambique during and after the end of the Civil War
(Springer Science and Business Media LLC, 2011-05-26)
Background: In recent years, vigorous debate has developed concerning how conflicts contribute to the spread of infectious diseases, and in particular, the role of post-conflict situations in the epidemiology of HIV/AIDS. ...
Quantitation of Plasmodium falciparum sporozoites transmitted in vitro by experimentally infected Anopheles gambiae and Anopheles stephensi
(American Society of Tropical Medicine and Hygiene, 1991)
The frequency and numbers of Plasmodium falciparum sporozoites transmitted in vitro and corresponding sporozoite loads were determined for experimentally infected Anopheles gambiae and An. stephensi. Geometric mean (GM) ...
Sporogonic development of cultured Plasmodium falciparum in six species of laboratory-reared Anopheles mosquitoes
(American Society of Tropical Medicine and Hygiene, 1994)
Sporogonic development of cultured Plasmodium falciparum was compared in six species of Anopheles mosquitoes. A reference species, A. gambiae, was selected as the standard for comparison. Estimates of absolute densities ...
Plasmodium falciparum: The population structure of mature gametocyte cultures has little effect on their innate fertility
(Elsevier BV, 1994)
In vitro cultured Plasmodium falciparum gametocytes were fed to Anopheles gambiae (G3) mosquitoes to identify parasite population characteristics useful for predicting successful mosquito infections. Parameters were collected ...
Exflagellation responses of cultured Plasmodium falciparum (Haemosporida: Plasmodiidae) gametocytes to human sera and midguts of anopheline mosquitoes (Diptera: Culicidae)
(Oxford University Press (OUP), 1994)
The process of exflagellation was quantified for cultured Plasmodium falciparum gametocytes exposed to human sera and midgut homogenates from six vector species of Anopheles mosquitoes. Neither serum factors related to ...
Immunological factor that affects Anopheles gambiae survival
(The American Mosquito Control Association, 1995)
High titers of antibodies against Anopheles gambiae midguts were produced in New Zealand rabbits to identify midgut targets for an antimosquito vaccine. The serum from one of 8 rabbits (designated R2B6) killed 71.6% (Abbott's ...
Mycobacteria, metals, and the macrophage
(Wiley, 2015-03)
Mycobacterium tuberculosis is a facultative intracellular pathogen that thrives inside host macrophages. A key trait of M. tuberculosis is to exploit and manipulate metal cation trafficking inside infected macrophages to ...
Invasive plants as foci of mosquito-borne pathogens: Red cedar in the southern Great Plains of the USA
(Springer Science and Business Media LLC, 2021-10-05)
West Nile virus (WNV) is the most significant mosquito-borne disease affecting humans in the United States. Eastern redcedar (ERC) is a native encroaching plant in the southern Great Plains that greatly alters abiotic ...
Protein complex from human milk enhances the activity of antibiotics and drugs against Mycobacterium tuberculosis.
(American Society for Microbiology, 2019-02)
Mycobacterium tuberculosis, the causative agent of human tuberculosis (TB), has surpassed HIV/AIDS as the leading cause of death from a single infectious agent. The increasing occurrence of drug-resistant strains has become ...