Browsing OSU - Faculty and Staff Publications by Subject "bacterial proteins"
Now showing items 1-7 of 7
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Coxiella burnetii Nine Mile II proteins modulate gene expression of monocytic host cells during infection
(BioMed Central, 2010-09-20)Background: Coxiella burnetii is an intracellular bacterial pathogen that causes acute and chronic disease in humans. Bacterial replication occurs within enlarged parasitophorous vacuoles (PV) of eukaryotic cells, the ... -
Evidence for alternative quaternary structure in a bacterial Type III secretion system chaperone
(BioMed Central, 2010-07-15)Background: Type III secretion systems are a common virulence mechanism in many Gram-negative bacterial pathogens. These systems use a nanomachine resembling a molecular needle and syringe to provide an energized conduit ... -
Heme and hemoglobin utilization by Mycobacterium tuberculosis
(Springer Nature, 2019-09-18)Iron is essential for growth of Mycobacterium tuberculosis (Mtb), but most iron in the human body is stored in heme within hemoglobin. Here, we demonstrate that the substrate-binding protein DppA of the inner membrane Dpp ... -
Identification of Campylobacter jejuni genes contributing to acid adaptation by transcriptional profiling and genome-wide mutagenesis
(American Society for Microbiology, 2008-03)In order to cause disease, the food- and waterborne pathogen Campylobacter jejuni must face the extreme acidity of the host stomach as well as cope with pH fluctuations in the intestine. In the present study, C. jejuni ... -
Novel approach to identify inhibitors of iron acquisition systems of Pseudomonas aeruginosa
(American Society for Microbiology, 2022-07-13)Pseudomonas aeruginosa is an opportunistic pathogen that has been declared by the World Health Organization as a “priority 1 critical pathogen” needing immediate new strategies for chemotherapy. During infection, P. ... -
Prevalence and genotypes of Anaplasma species and habitat suitability for ticks in a Mediterranean ecosystem
(American Society for Microbiology, 2008-12)Anaplasma species are tick-transmitted pathogens that impact veterinary and human health. Sicily is one of the locations where these pathogens are endemic. Sicily represents a typical Mediterranean ecosystem to study ... -
Sp110 transcription is induced and required by Anaplasma phagocytophilumfor infection of human promyelocytic cells
(BioMed Central, 2007-09-20)Background: The tick-borne intracellular pathogen, Anaplasma phagocytophilum (Rickettsiales: Anaplasmataceae) causes human granulocytic anaplasmosis after infection of polymorphonuclear leucocytes. The human Sp110 gene is ...