Now showing items 1-4 of 4

    • Genome-wide screen identifies a single B-defensin gene cluster in the chicken: Implications for the origin and evolution of mammalian defensins 

      Xiao, Yanjing; Hughes, Austin L.; Ando, Junko; Matsuda, Yoichi; Cheng, Jan-Fang; Skinner-Noble, Donald; Zhang, Guolong (BioMed Central, 2004-08-13)
      Background: Defensins comprise a large family of cationic antimicrobial peptides that are characterized by the presence of a conserved cysteine-rich defensin motif. Based on the spacing pattern of cysteines, these defensins ...
    • Genomic data for 78 chickens from 14 populations 

      Li, Diyan; Che, Tiandong; Chen, Binlong; Tian, Shilin; Zhou, Xuming; Zhang, Guolong; Li, Miao; Gaur, Uma; Li, Yan; Luo, Majing; Zhang, Long; Xu, Zhongxian; Zhao, Xiaoling; Yin, Huadong; Wang, Yan; Jin, Long; Tang, Qianzi; Xu, Huailiang; Yang, Mingyao; Zhou, Rongjia; Li, Ruiqiang; Zhu, Qing; Li, Mingzhou (Oxford University Press, 2017-06)
      Background: Since the domestication of the red jungle fowls (Gallus gallus; dating back to~10 000 B.P.) in Asia, domestic chickens (Gallus gallus domesticus) have been subjected to the combined effects of natural selection ...
    • Nutrients mediate intestinal bacteria-mucosal immune crosstalk 

      Ma, Ning; Guo, Pingting; Zhang, Jie; He, Ting; Kim, Sung Woo; Zhang, Guolong; Ma, Xi (Frontiers Media, 2018-01-24)
      The intestine is the shared site of nutrient digestion, microbiota colonization and immune cell location and this geographic proximity contributes to a large extent to their interaction. The onset and development of a great ...
    • Rattusin, an intestinal a-defensin-related peptide in rats with a unique cysteine spacing pattern and salt-insensitive antibacterial activities 

      Patil, Amar A.; Ouellette, Andre J.; Lu, Wuyuan; Zhang, Guolong (American Society for Microbiology, 2013-04)
      Cationic antimicrobial peptides are essential components of the innate immune system. As a major family of mammalian antimicrobial peptides, defensins are expressed mainly by mucosal epithelial cells and promyelocytes. ...