Now showing items 1-3 of 3

    • Arsenic-induced changes in the gene expression of lung epithelial L2 cells: Implications in carcinogenesis 

      Posey, Tisha; Weng, Tingting; Chen, Zhongming; Chintagari, Narendranath R.; Wang, Pengcheng; Jin, Nili; Stricker, Heidi; Liu, Lin (BioMed Central, 2008-03-03)
      Background: Arsenic is a carcinogen that is known to induce cell transformation and tumor formation. Although studies have been performed to examine the modulation of signaling molecules caused by arsenic exposure, the ...
    • miR-27b inhibits fibroblast activation via targeting TGFB signaling pathway 

      Zeng, Xiangming; Huang, Chaoqun; Senavirathna, Lakmini; Wang, Pengcheng; Liu, Lin (BioMed Central, 2017-01-17)
      Background: MicroRNAs are a group of small RNAs that regulate gene expression at the posttranscriptional level. They regulate almost every aspect of cellular processes. In this study, we investigated whether miR-27b regulates ...
    • Proteomic analysis of lamellar bodies isolated from rat lungs 

      Wang, Pengcheng; Chintagari, Narendranath Reddy; Narayanaperumal, Jeyaparthasarathy; Ayalew, Sahlu; Hartson, Steven; Liu, Lin (BioMed Central, 2008-06-24)
      Background: Lamellar bodies are lysosome-related secretory granules and store lung surfactant in alveolar type II cells. To better understand the mechanisms of surfactant secretion, we carried out proteomic analyses of ...