Browsing OSU - Faculty and Staff Publications by Author "Alberdi, Pilar"
Now showing items 1-8 of 8
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Anaplasma phagocytophilum infection subverts carbohydrate metabolic pathways in the tick vector, Ixodes scapularis
Cabezas-Cruz, Alejandro; Alberdi, Pilar; Valdes, James J.; Villar, Margarita; Fuente, Jose de la (Frontiers Media, 2017-02-07)The obligate intracellular pathogen, Anaplasma phagocytophilum, is the causative agent of human, equine, and canine granulocytic anaplasmosis and tick-borne fever (TBF) in ruminants. A. phagocytophilum has become an emerging ... -
Anaplasma phagocytophilum MSP4 and HSP70 proteins are involved in interactions with host cells during pathogen infection
Contreras, Marinela; Alberdi, Pilar; Mateos-Hernandez, Lourdes; Fernandez de Mera, Isabel G.; Garcia-Perez, Ana L.; Vancova, Marie; Villar, Margarita; Ayllon, Nieves; Cabezas-Cruz, Alejandro; Valdes, James J.; Stuen, Snorre; Gortazar, Christian; de la Fuente, Jose (Frontiers Media, 2017-07-05)Anaplasma phagocytophilum transmembrane and surface proteins play a role during infection and multiplication in host neutrophils and tick vector cells. Recently, A. phagocytophilum Major surface protein 4 (MSP4) and Heat ... -
Effect of blood type on anti-a-Gal immunity and the incidence of infectious diseases
Cabezas-Cruz, Alejandro; Mateos-Hernandez, Lourdes; Alberdi, Pilar; Villar, Margarita; Riveau, Gilles; Hermann, Emmanuel; Schacht, Anne-Marie; Khalife, Jamal; Correia-Neves, Margarida; Gortazar, Christian; de la Fuente, Jose (Nature Publishing Group, 2017-03-10)The identification of factors affecting the susceptibility to infectious diseases is essential toward reducing their burden on the human population. The ABO blood type correlates with susceptibility to malaria and other ... -
Ixodes scapularis tick cells control Anaplasma phagocytophilum infection by increasing the synthesis of phosphoenolpyruvate from tyrosine
Cabezas-Cruz, Alejandro; Espinosa, Pedro J.; Obregon, Dasiel A.; Alberdi, Pilar; de la Fuente, Jose (Frontiers Media, 2017-08-17)The obligate intracellular pathogen, Anaplasma phagocytophilum, is the causative agent of life-threatening diseases in humans and animals. A. phagocytophilum is an emerging tick-borne pathogen in the United States, Europe, ... -
Tick vaccines and the control of tick-borne pathogens
Merino, Octavio; Alberdi, Pilar; Perez de la Lastra, Jose M.; de la Fuente, Jose (Frontiers Media, 2013-07-09)Ticks are obligate hematophagous ectoparasites that transmit a wide variety of pathogens to humans and animals. The incidence of tick-borne diseases has increased worldwide in both humans and domestic animals over the past ... -
Tick-pathogen interactions and vector competence: Identification of molecular drivers for tick-borne diseases
de la Fuente, Jose; Antunes, Sandra; Bonnet, Sarah; Cabezas-Cruz, Alejandro; Domingos, Ana G.; Estrada-Pena, Agustin; Johnson, Nicholas; Kocan, Katherine M.; Mansfield, Karen L.; Nijhof, Ard M.; Papa, Anna; Rudenko, Nataliia; Villar, Margarita; Alberdi, Pilar; Torina, Alessandra; Ayllon, Nieves; Vancova, Marie; Golovchenko, Maryna; Grubhoffer, Libor; Caracappa, Santo; Fooks, Anthony R.; Gortazar, Christian; Rego, Ryan O. M. (Frontiers Media, 2017-04-07)Ticks and the pathogens they transmit constitute a growing burden for human and animal health worldwide. Vector competence is a component of vectorial capacity and depends on genetic determinants affecting the ability of ... -
Tissue-specific signatures in the transcriptional response to Anaplasma phagocytophilum infection of Ixodes scapularis and Ixodes ricinus tick cell lines
Alberdi, Pilar; Mansfield, Karen L.; Manzano-Roman, Raul; Cook, Charlotte; Ayllon, Nieves; Villar, Margarita; Johnson, Nicholas; Fooks, Anthony R.; de la Fuente, Jose (Frontiers Media, 2016-02-10)Anaplasma phagocytophilum are transmitted by Ixodes spp. ticks and have become one of the most common and relevant tick-borne pathogens due to their impact on human and animal health. Recent results have increased our ... -
Vaccinomics approach to the identification of candidate protective antigens for the control of tick vector infestations and Anaplasma phagocytophilum infection
Contreras, Marinela; Alberdi, Pilar; Fernandez de Mera, Isabel G.; Krull, Christoph; Nijhof, Ard; Villar, Margarita; de la Fuente, Jose (Frontiers Media, 2017-08-09)Anaplasma phagocytophilum is an emerging tick-borne pathogen causing human granulocytic anaplasmosis (HGA), tick-borne fever (TBF) in small ruminants, and other forms of anaplasmosis in different domestic and wild animals. ...