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Efficacy of a doxycycline treatment regimen initiated during three different phases of experimental ehrlichiosis
(American Society for Microbiology, 2010-12)
Doxycycline is the treatment of choice for canine monocytic ehrlichiosis (CME), a well-characterized disease and valuable model for tick-borne zoonoses. Conflicting reports of clearance of Ehrlichia canis after treatment ...
Rattusin, an intestinal a-defensin-related peptide in rats with a unique cysteine spacing pattern and salt-insensitive antibacterial activities
(American Society for Microbiology, 2013-04)
Cationic antimicrobial peptides are essential components of the innate immune system. As a major family of mammalian antimicrobial peptides, defensins are expressed mainly by mucosal epithelial cells and promyelocytes. ...
In vitro efficacy of antibiotics commonly used to treat human plague against intracellular Yersinia pestis
(American Society for Microbiology, 2011-08)
Yersinia pestis initiates infection as a facultative intracellular parasite in host macrophages; however, little is known about the efficacy of antibiotics commonly used to treat human plague against intracellular Y. pestis. ...