Recombinant Antigen Msp1a from Anaplasma Marginale to Reduce Infections in Ticks, Vaccine Compositions and Methods of Use
![Thumbnail](/bitstream/handle/11244/15389/pat6979451.pdf.jpg?sequence=9&isAllowed=y)
View/ Open
Date
2005-12-27Author
Fuente, Jose de la
Kocan, Katherine M.
Garcia-Garcia, Jose Carlos
Blouin, Edmour F.
Board of Regents/Oklahoma State University and the A & M Colleges
Metadata
Show full item recordAbstract
Vaccines and methods for inducing an immune response in a ruminant. The vaccine composition including pathogen and tick-derived antigens and a carrier or diluent. The method for inducing an immune response in a ruminate to provide immune protection which reduces the infection of ticks by A. marginale and/or prevents the transmission of the pathogen includes the steps of administering to the ruminant an effective amount of the vaccine composition having at least one antigen member of the group comprising at least one antigen member of the group comprising (i) recombinant MSP1a surface protein antigen of A. marginale, (ii) a subunit of recombinant MSP1a surface protein antigen of A. marginale and (iii) recombinant MSP1a surface protein antigen or subunits thereof in combination with antigen preparation derived from A. marginale infected cultured tick IDE8 cells and/or other pathogen and tick-derived antigens, and a carrier or diluent.
Collections
- Patents [208]