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Primer-extension Based Method for the Generation of Sirna/mirna Expression Vectors
(U.S. Patent and Trademark Office, 2014-08-05)
Functional shRNA is produced from an expression vector prepared by selecting a two primer design in which the primers are less than about 50 nucleotides in length, annealing and extending the primers using primer extension, ...
Immunogenic Compositions, Vaccines and Diagnostics Based on Canine Distemper Viruses Circulating in North American Dogs
(U.S. Patent and Trademark Office, 2014-02-11)
Immunogenic compositions and broad-spectrum vaccines containing newly identified isolates of canine distemper virus (CDV) collected from a geographic area are provided. The newly identified isolates exhibit attributes of ...