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Sequence and analysis of Actinobacillus actinomycetemcomitans.
(2002)
A. actinomycetemcomitans is a Gram negative coccobacillus, facultative anaerobe that is implicated in the persistence of peridontitis, the destruction of the gum tissues and loss of teeth (Fives-Taylor et al, 1999). In an ...
Low-molecular-weight branched polyethylenimines: Multifunctional beta-lactam potentiators against resistant Gram-negative pathogens
(2022-05-13)
Antibiotic resistance is a simmering threat to the global public health system. Currently, it is estimated by the Centers for Disease Control and Prevention that at least 2.8 million people in the US get infected with ...
Conformational dynamics and structure of FepA, a ligand-gated channel in the bacterial outer membrane.
(1998)
Since Waring & Werkman documented a microbial requirement for iron in 1944, much progress has been made in understanding how microbes assimilate this mundane but biological precious metal. The proteins involved in iron ...
Purification, Mechanism, and Biochemical Interactions of the Essential Mycolic Acid Transporters MmpL3 from Mycobacterium tuberculosis, and CmpL1 from Corynebacterium glutamicum.
(2020-06)
The Corynebacterium – Mycobacterium – Nocardia family (CMN family) are a subset group of actinomycetes which are characterized as acid-fast, Gram-positive species. Many members of the CMN family are causative agents of ...
Characterization of a Sporulation Related Two-Component Signaling System in Clostridioides difficile
(2023-12-15)
Clostridioides difficile is a spore-forming anaerobic human pathogen, that is commonly associated with antibiotic therapy in adults. The disturbance of the gut microbiota, typically caused by antibiotics, allows for an ...
Iron uptake in Gram-negative and Gram-positive bacteria.
(2006)
Bacteria, including both Gram-positive and Gram-negative bacteria, utilize iron sources from the environment. Iron uptake systems in Gram-negative bacteria are well studied. Escherichia coli FepA transports certain catecholate ...
Stressed Out: Resistance-nodulation-division (RND) and Major Facilitator Superfamily (MFS) Efflux Pump Mediated Survival Strategies of Acinetobacter baumannii
(2024-05-11)
Originally discovered in soil microbial communities, reports of genus Acinetobacter associated infections started to increase around 1977 and continued to climb to frightening heights for the next 20 years resulting in ...