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BIONANOFIBER-BASED NANOSTRUCTURE FABRICATION AND APPLICATIONS
(2017-12)
Among various strategies for the synthesis and assembly of nano-scaled structures, bio-templating is an efficient method due to the unique physical and chemical properties of the template bionanomaterials, thus has experienced ...
Chemical Modeling of Unstable Intermediates in Heme-mediated NOx Biology
(2017-05-12)
This dissertation describes the preparation, characterization, and reactivity of several critical unstable intermediates of relevance to the global N-cycle. Their spectroscopic signatures and chemical reactivities were ...
The Effect Of Ligand Denticity In Stabilizing Actinide-Element Multiple Bond Functionalities
(2017-12)
Different synthetic approaches to the development of complexes with X-An=E and E=An=E functionalities (where An = U, Th) for use in studying the inverse trans influence (ITI) and the role f-orbitals play in early actinide ...
Capillary-based analytical technique developments for analysis of bio-sample
(2017-05)
Analytical chemistry plays a significant role in bioscience research. Bio-samples, such as DNA and proteins, are often used for identification purpose or disease related research. Analyzing a biological sample typically ...
DEVELOPING ELECTROOSMOTIC-PUMP-BASED MINIATURIZED DEVICES: TOWARD A LIQUID CHROMATOGRAPHY CARTRIDGE COUPLED WITH MASS SPECTROMETER AND A SUB-PICOLITER PIPETTOR FOR SINGLE CELL SURGERY
(2017-06)
There has been increasing interest on miniaturizing high performance liquid chromatography (HPLC), since it can reduce the costs of instrument manufacturing and perform onsite analysis. The electroosmotic pump (EOP) is one ...
HOST-GUEST COMPLEXATION OF BENZYL AND XYLYL AMMONIUM GUESTS WITH CUCURBIT[7]URIL FOR SHUTTLE ROTAXANES
(2017-12)
Bistable rotaxanes are considered to be important design elements of molecular devices for a wide range of applications, such as controlled drug release, molecular machines, and molecular sensors and shuttles. The interest ...
Differential Contributions of Outer Membrane Permeability and Active Efflux in Physiology and Drug Susceptibility of Gram-Negative Bacteria
(2017-12-15)
The increased frequency of antibiotic resistant bacterial isolates is of great concern for public health. It is currently estimated that infections caused by multidrug resistant pathogens will surpass cancer as a leading ...
A Computational Study of Amyloid Fibrils and their Structural Properties
(2017-12)
The term amyloid describes misfolded protein aggregates in which a highly ordered cross β-sheet pattern is adopted. While there exist functional amyloids, the majority of known amyloids are associated with diseases in ...
Discovery of the molecular interactions mediating malaria transmission in the mosquito midgut
(2017)
Malaria is a worldwide health problem that affects two thirds of the world population and kills approximately one million people annually. Infecting Anopheline mosquitoes is the essential step for malaria transmission. ...
Chromosome Organization and Segregation in Pseudomonas Aeruginosa
(2017-12)
The faithful propagation of genetic information from a mother to its progeny is one of the most fundamental aspects of life. Encoding the entirety of an organisms' genetic information onto chromosomes poses a unique set ...