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Diffuse Optical Tomography of Spontaneous Brain Fluctuations in Humans
(2022-05-13)
In the absence of tasks or external stimuli, the human brain produces recordable spontaneous low-frequency fluctuating hemodynamic signals, which show temporally-correlated activity among brain regions forming a so-called ...
A novel polysaccharide-based surface engineering strategy for nanomedicines
(2022-08-04)
This dissertation presents the development and evaluation of a novel polysaccharide-based surface engineering strategy for nanomedicines.
Chapter one summaries the current status of nanoparticle toxicology. Nanoparticles ...
Engineering a peptide-based tool for biomedical applications
(2022-12-16)
Numerous technological and scientific advancements have been developed by the structural organization and functional capabilities of natural materials. A field known as "biomaterials" focuses on adapting engineering concepts ...
Peptide Aggregation Induced Immunogenic Cell Death
(2022-12-16)
Cell death is an inevitable biological outcome, every living thing dies. However, how cells die is an important question and ultimately is decisive in homeostasis and disease progression. Immune system is in the center of ...
Mapping brain activity and resting-state functional connectivity with functional near-infrared spectroscopy
(2022-08-04)
Functional near-infrared spectroscopy (fNIRS) as a non-invasive optical imaging technique to measure cerebral hemodynamics has seen rapid development and increasing use in studying the human brain. fNIRS measures relative ...
Translation and Development of Novel Annexin A5 - Protein Drug Conjugates for the Treatment of Triple-Negative Breast Cancer
(2022-12-16)
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subset with limited targeted chemotherapies. TNBC is defined by the absence of the estrogen, progesterone, and HER2 hormonal receptors on the cell ...