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Mining Microbial Communities: Exploring Symbiotic Bacteria as a Source of New Natural Products
(2013)
As ubiquitous inhabitants of Earth, bacteria represent a diverse resource in the search for new natural products. In order for the field of natural products to progress, new and exciting sources of biodiversity must be ...
STUDIES OF THE USE OF THE [2.2]PARACYCLOPHANE MOIETY TO MEDIATE INTERACTION BETWEEN METAL CENTERS AND ELECTROPOLYMERIZATION OF 2,2’-BITHIOPHENE IN MICELLAR MEDIA
(2013)
Organometallic polymers have been identified as a class of materials useful in various advanced applications due to their promising electrical, magnetic, optical and catalytic properties. Such properties depend on the ...
Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter
(2013)
In Gram-negative bacteria, intrinsic antibiotic resistance is provided by three component efflux transporters. In Escherichia coli, MacAB-TolC is the first experimentally described ATP-driven tripartite efflux pump responsible ...
Imitating Nature: The Effects of Asymmetry and Strain on Copper and Iron Complexes with Schiff Base Ligands
(2013)
Metalloenzymes are incredibly complex "machines" which catalyze reactions essential for life. Metal ions are found in more than half of all known proteins; particularly, copper and iron are abundant in active sites performing ...
Determining Conformational Change within the Escherichia coli Outer Membrane Protein FepA
(2013)
Bacteria have been able to circumvent antibiotic treatment in several ways, e.g., reorganization of the membrane and its permeability, decrease porin content, over expression of efflux pumps, and genetic changes in target ...
Design and Synthesis of NIR BODIPY Dyes: Application for In Vivo Fluorescence Imaging and Photodynamic Therapy
(2013)
DESIGN AND SYNTHESIS OF NIR BODIPY DYES: APPLICATION FOR IN VIVO FLUORESCENCE IMAGING AND PHOTODYNAMIC THERAPY
The Nature of Water in Bacterial Spores, Sporicidal Activity of Chlorine Dioxide, and Cryoprotectant Properties of Poly(adenylic) Acid
(2013)
Water is the fundamental chemical molecule of life, and the nature of how water interacts with living organisms and how living organisms can maintain liquid water for metabolic function below freezing (cryoprotection) is ...
Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter
(2013)
In Gram-negative bacteria, intrinsic antibiotic resistance is provided by three component efflux transporters. In Escherichia coli, MacAB-TolC is the first experimentally described ATP-driven tripartite efflux pump responsible ...
The Nature of Water in Bacterial Spores, Sporicidal Activity of Chlorine Dioxide, and Cryoprotectant Properties of Poly(adenylic) Acid
(2013)
Water is the fundamental chemical molecule of life, and the nature of how water interacts with living organisms and how living organisms can maintain liquid water for metabolic function below freezing (cryoprotection) is ...
BIOLOCIAL EVALUATION OF MITOCHONDRIA-TARGETING PHOTOSENSTIZERS AND SITE-SPECIFIC PRODRUGS
(2013)
This dissertation focuses on two different delivery mechanisms utilizing the principle of PDT with a goal to enhance the availability of the cytotoxic agent at the tumor site.