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A bioinorganic approach to the study of the interactions of nitrogen oxides with manganese porphyrins and manganese- and cobalt-reconstituted myoglobin.
(2007)
This dissertation deals with the interaction of the biologically important nitrogen oxides (nitric oxide and nitrite) with manganese and ruthenium centers in small inorganic porphyrin and nonporphyrin complexes as well as ...
Differential pulse voltammetric oxidation of polyinosinic acid and its components
(1983)
Oxidation of 6-methyl-5,6,7,8-tetrahydropterin (6-MTHP) and 6-methyl-5,6,7,8-dihydropterin (6-MDHP) was studied using electrochemical techniques. 6-MTHP is electrolyzed in a 2e-2H('+) quasi-reversible process to an unstable ...
Polyviologen-modified anodes for carbohydrate biofuel cells
(2021-05-14)
Polyalkylviologens (PVCn (n = 2 - 6)) were successfully deposited on glassy carbon electrodes (GCEs) by electropolymerization of bis(4-cyano-1-pyridino)-alkane dibromides (PyCnBr2 (n = 2 - 6)) as precursors. By studying ...
Nuclear Magnetic Resonance Study of Nucleic Acid Tertiary Structures
(2011)
Ribonucleic acid (RNA) is ubiquitous to all organisms and a molecule that essential to all life forms. RNA is a versatile molecule with numerous cellular functions. With advances in nucleic acid sequencing, researchers ...
Personalized medicine: developing precision antiviral/ anticancer therapeutics and bio-analytical chemotherapeutic drug monitoring
(2020)
Personalized medicine, also known as precision medicine, is a broad medical paradigm for tailoring patients’ treatments based upon their individual biological makeup to produce the most effective, safest clinical outcomes. ...
Accessing Natural Products from Silent Biosynthetic Pathways Using Chemical Epigenetics
(2011)
Natural products have played a major role in the history of medicine. Despite this history, many view the area of natural products discovery to be tapped dry, thus the focus of drug development companies has shifted towards ...
Bacteriophage-based biomaterials for manipulating derivation and differentiation of human induced pluripotent stem cells
(2020-05)
Induced pluripotent stem cells (iPSCs), which are derived from somatic cells, can differentiate into any cell type. They are promising tools in medical applications including regenerative medicine, personalized cell therapy, ...