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Fiber-Optic Infrared Spectroelectrochemistry of Some Dinitrosyl Iron Phosphine Complexes and an NMR Kinetics and Equilibrium Study of an Organic Nitroso Compound in Various Solvents
(2010)
This dissertation describes a study of some of the fundamental chemical properties of some dinitrosyl iron phosphine complexes and a study of the dimer-monomer equilibrium of 2-methyl-2-nitrosopropane in various solvents.
TARGETING PLASMODIUM INVASION PATHWAYS IN MOSQUITOES TO BLOCK MALARIA TRANSMISSION
(2016-12)
Malaria remains a devastating disease. Transmission-blocking vaccines (TBVs) are being considered as a promising approach to eliminate Plasmodium infection. However, the challenges in developing such a vaccine are paramount, ...
Discovery of the molecular interactions mediating malaria transmission in the mosquito midgut
(2017)
Malaria is a worldwide health problem that affects two thirds of the world population and kills approximately one million people annually. Infecting Anopheline mosquitoes is the essential step for malaria transmission. ...
BIOLOGICAL IMPLICATIONS OF THE REACTIONS OF THIOCYANATE (SCN
(2011)
Hypochlorous acid (HOCl) is one of the major neutrophil-derived oxidants used to kill invading pathogens. However, excess or misplaced production of HOCl can damage host tissue as it reacts indiscriminately with biological ...
SYNTHESIS AND REDOX BEHAVIOR OF GROUP 8 METALLOPORPHYRINS AND RELATED COMPOUNDS
(2015)
This dissertation describes the Chemistry of Group 8 Metalloporphyrins and related compounds. Chapter one describes linkage isomerization in NOx-coordinated metal complexes with emphasis on Group 8 metals, and part of this ...
Nuclear Magnetic Resonance Study of Nucleic Acid Tertiary Structures
(2011)
Ribonucleic acid (RNA) is ubiquitous to all organisms and a molecule that essential to all life forms. RNA is a versatile molecule with numerous cellular functions. With advances in nucleic acid sequencing, researchers ...
Mutational Analysis of Bacterial Condensins
(2011)
Genetic information is carried on chromosomes in all organisms and chromosome is at the center of all life processes. The chromosome must be properly folded to fit into the cells. Moreover, replication and segregation of ...
CONSTANT-pH MOLECULAR DYNAMICS SIMULATIONS: DEVELOPMENT AND APPLICATIONS
(2012)
Constant-pH molecular dynamics has recently emerged as a useful technique for studying the microscopic details underlying pH dependent properties of proteins. We further develop continuous constant-pH molecular dynamics ...
Roles of Unique Membrane Fusion Proteins
(2015-11)
One of the primary mechanisms of antibiotic resistance in bacteria stems from the expression of multicomponent efflux transporters, located in the membranes of both Gram-positive and Gram-negative bacteria. Although these ...
Study of Silica Sol-Gel Materials for Sensor Development
(2010)
As a widely-explored subject for numerous applications, silica sol-gel has attracted