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Now showing items 21-30 of 44
Synthesis, structure, and solution properties of benzoannelated cryptands.
(2006)
Cryptands An2.2.1 and An2.2.2 were synthesized by high dilution techniques. Attempts to produce An3.1.1 gave primarily the 2 + 2 addition product An3.1.1.3. X-ray crystallography, ESI-MS, and NMR techniques were used to ...
Investigations of the effects of iron, manganese, and nickel on the properties of sulfated zirconia catalysts.
(1997)
Thermogravimetry (TG) was utilized to study catalyst thermal stability and to measure sulfate contents for catalysts with differing compositions. Temperature programmed desorption (TPD) measurements of surface adsorbed ...
Titanocene-catalyzed stereoselective couplings of aldehydes.
(1999)
A catalytic pinacol reaction that was enantioselective was also of interest. Three chiral titanium complexes possessed tethers: Brintzinger's catalyst or ethylenebis-(4,5,6,7-tetrahydroindenyl) titanium dichloride 1, (1S, ...
Concise synthesis methods to aminosterols and sterol N-glycosides for the development of new OSW-1-derived scaffolds
(2020-05-08)
Abstract
The cholestane glycoside natural product compound OSW-1 has both broad spectrum antiviral activity and potent antiproliferative activity. OSW-1 is a high affinity ligand of both oxysterol-binding protein (OSBP) ...
Regulation of conformational interconversions in symmetric and asymmetric [2]catenanes.
(2006)
Using non-biasing tethers, consisting of phenyl rings designed to be blocking or non-blocking in nature, we were able to control the pathway for interconversion. Through the appropriate incorporation of blocking groups on ...
HOST-GUEST COMPLEXATION OF BENZYL AND XYLYL AMMONIUM GUESTS WITH CUCURBIT[7]URIL FOR SHUTTLE ROTAXANES
(2017-12)
Bistable rotaxanes are considered to be important design elements of molecular devices for a wide range of applications, such as controlled drug release, molecular machines, and molecular sensors and shuttles. The interest ...
Nitrosyl and nitroso complexes of group 8 metalloporphyrins.
(1998)
Chapter 3 of this dissertation describes the synthesis and characterization of osmium nitrosyl porphyrins containing organo, chloro and $\mu$-oxo ligands and the extensions of the synthetic methodology to the preparation ...
HARNESSING SMALL-MOLECULE PROTEIN STIMULATION TO DEVELOP NEW LEADS FOR RETINAL AND INFECTIOUS DISEASES
(2020-07)
This dissertation describes the development of new therapeutic leads for retinal (chapter 1-3) and infectious diseases (chapter 4). More than 40% of patients with retinal inflammatory diseases are refractory to the standard ...