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Now showing items 111-120 of 123
IMMUNODOMINANCE OF ANTIGENIC SITE B IN RECENT CIRCULATING H3N2 INFLUENZA VIRUSES
(2012)
Type A influenza viruses cause seasonal epidemics and global pandemics driven by antigenic drift in the viral surface glycoproproteins, hemagglutinin (HA) and neuraminidase (NA). Each year in the United States more than ...
BACTERIAL FLAGELLA TEMPLATED SYNTHESIS OF HYBRID NANOMATERIALS BY BIOMIMETIC MINERALIZATION IN MILD CONDITIONS
(2011)
Biological template directed nanomaterials have unique properties. Under genetic control, they can specifically interact with other macromolecules or inorganics. Moreover, the biologically based materials are easily assembled ...
Single-probe Mass Spectrometry as a Bioanalytical Tool for Quantitative Single Cell Analysis: From Cell Lines to Patients
(2019-05-10)
Cellular processes are traditionally characterized using bulk analysis. However, cell population averaging techniques are unable to accurately characterize these processes as each cell is extremely heterogeneous and can ...
SYNTHESIS, ISOLATION, AND REACTIVITY OF KINETICALLY STABILIZED AROMATIC NITROSAMIDES AND NEW LOW DIMENSIONAL ORGANIC INORGANIC HYBRID MATERIALS
(2019-08-01)
The conversion of aromatic amines to esters and phenols is a useful transformation typically carried out using diazonium salt intermediates, but the yields can vary wildly. It has been demonstrated that the reaction of ...
COPPER CHEMISTRY OF PYRIDYLALKYLBENZAMIDE LIGANDS: MODELING THE CUZ CENTER OF N2OR AND COORDINATION POLYMER CHEMISTRY
(2011)
In nature, the reduction of N2O to N2 is the terminal step of the denitrification process, which is catalyzed by nitrous oxide reductase (N2OR). The catalytic CuZ center was found to be a novel μ4-sulfide bridged ...
VIRUS-SELECTED OSTEOGENESIS-INDUCING PEPTIDES FOR ENHANCED BONE REGENERATION IN 3D PRINTED TITANIUM ALLOY IMPLANTS
(2018-12-14)
Bone morphogenetic proteins (BMPs) are part of the transforming growth factor-β superfamily and function as key regulators of cellular growth, differentiation, and tissue formation. While recombinant BMPs can be used to ...
Interaction of Metal Ions with the Polyanionic Gram-Positive Cell Wall and the Effect of Antimicrobial Cationic Branched Polyethyleneimine on Metal Binding
(2014-12)
Metal binding is a known characteristic of the bacterial cell wall. Yet, the binding mechanisms and affinity constants are not fully understood. The cell wall of Gram-positive bacteria is characterized by a thick layer of ...
Nuclear Magnetic Resonance Study of Nucleic Acid Tertiary Structures
(2011)
Ribonucleic acid (RNA) is ubiquitous to all organisms and a molecule that essential to all life forms. RNA is a versatile molecule with numerous cellular functions. With advances in nucleic acid sequencing, researchers ...
Accessing Natural Products from Silent Biosynthetic Pathways Using Chemical Epigenetics
(2011)
Natural products have played a major role in the history of medicine. Despite this history, many view the area of natural products discovery to be tapped dry, thus the focus of drug development companies has shifted towards ...
Role of the outer membrane channel TolC in physiology of Escherichia coli
(2010)
TolC is a versatile, multifunctional protein and in Gram-negative bacteria such as E.coli, it has been shown to participate in several functions like drug efflux, toxin secretion and has also been demonstrated to be important ...