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Structural and Optical Properties of All-Inorganic and Hybrid Organic-Inorganic Metal (M = Zn, Cd, Hg, Cu) Halides
(2019)
All-inorganic and hybrid organic-inorganic metal halide materials, especially halide perovskites, have sparked the interest of the materials research community due to their excellent optoelectronic properties and their ...
Fiber-Optic Infrared Spectroelectrochemistry of Some Dinitrosyl Iron Phosphine Complexes and an NMR Kinetics and Equilibrium Study of an Organic Nitroso Compound in Various Solvents
(2010)
This dissertation describes a study of some of the fundamental chemical properties of some dinitrosyl iron phosphine complexes and a study of the dimer-monomer equilibrium of 2-methyl-2-nitrosopropane in various solvents.
TARGETING PLASMODIUM INVASION PATHWAYS IN MOSQUITOES TO BLOCK MALARIA TRANSMISSION
(2016-12)
Malaria remains a devastating disease. Transmission-blocking vaccines (TBVs) are being considered as a promising approach to eliminate Plasmodium infection. However, the challenges in developing such a vaccine are paramount, ...
Discovery of the molecular interactions mediating malaria transmission in the mosquito midgut
(2017)
Malaria is a worldwide health problem that affects two thirds of the world population and kills approximately one million people annually. Infecting Anopheline mosquitoes is the essential step for malaria transmission. ...
Structural and Functional Characterization of the Binding of C-nitroso Compounds to Myoglobin and Hemoglobin
(2019)
The formation and structural characterization of the interactions of the oxygen-carrier proteins myoglobin (Mb) and hemoglobin (Hb) with C-nitroso metabolites are described. The spectroscopic studies and X-ray crystal ...
BIOLOGICAL IMPLICATIONS OF THE REACTIONS OF THIOCYANATE (SCN
(2011)
Hypochlorous acid (HOCl) is one of the major neutrophil-derived oxidants used to kill invading pathogens. However, excess or misplaced production of HOCl can damage host tissue as it reacts indiscriminately with biological ...
RHODIUM CARBENOID INITIATED CASCADES FOR THE SYNTHESIS OF DIVERSE MEDIUM-SIZED HETEROCYCLES
(2019)
Medium-sized rings (8–12 membered) are a unique class of cyclic molecules. These structures are present within a plethora of relevant natural products often possessing enhanced pharmacokinetic properties due to their dynamic ...
Branched polyethylenimine re-sensitizes methicillin-resistant Staphylococcus aureus to beta-lactam antibioitics through a novel mechanism of action
(2018)
Methicillin-resistant Staphylococcus aureus (MRSA) is a growing concern in the medical industry due to high morbidity and difficulty of treatment in infected patients. Conventional β-lactam antibiotics kill Staphylococcus ...
SYNTHESIS AND REDOX BEHAVIOR OF GROUP 8 METALLOPORPHYRINS AND RELATED COMPOUNDS
(2015)
This dissertation describes the Chemistry of Group 8 Metalloporphyrins and related compounds. Chapter one describes linkage isomerization in NOx-coordinated metal complexes with emphasis on Group 8 metals, and part of this ...
Investigations of Secondary Metabolites from Fungi: Isolation, Structure Elucidation, and Computational Studies
(2018-12-14)
Natural products have served as therapeutic agents in the treatment of many human health ailments for thousands of years. In order to find new therapeutic agents for future human health problems, those in the field of ...