Browsing OU - Dissertations by Author "Safiejko-Mroczka, Barbara"
Now showing items 1-4 of 4
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Development and Preclinical Evaluation of Enzyme Prodrug Therapies Targeted to the Tumor Vasculature
Krais, John (2014)Breast cancer is a global health concern of high prevalence that lacks safe and effective therapies for advanced cases. A targeted enzyme prodrug therapy aims to address this issue using an enzyme localized to the tumor ... -
DEVELOPMENT OF BIOMATERIALS FOR CALVARIAL BONE REGENERATION AND APPLICATION TO TRAUMATIC BRAIN INJURY
Townsend, Jakob (2017)In the treatment of severe traumatic brain injury (TBI), a two-stage surgical intervention is routinely performed. In the first surgery, decompressive craniectomy (DC) is performed to remove a large portion of calvarial ... -
Phosphatidylserine Targeted Biotechnology Agents for Cancer
Virani, Needa (2017-08-16)Cancer is a highly mutating disease that quickly develops resistance to chemotherapies and has a high rate of relapse. If detected early, the survival rate is greater than 90% for most cancers; however if diagnosed during ... -
Wister Area Fourche Maline: A Contested Landscape
Rowe, Simone (2014-05-09)The Wister area of southeastern Oklahoma was a contested landscape during the Fourche Maline (Late Woodland cultural period). This claim is supported by paleopathological evidence for high rates of skeletal trauma and ...