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New age: Quantitative morphometry for the 21st century - Advances in the study of dorsal root ganglion neurons
(2021-12)
Dorsal root ganglion (DRG) neurons transduce sensory information in peripheral tissues, transmitting centrally as action potential frequency, along second and third order neurons for processing in the somatosensory cortex. ...
Apoptotic and bioenergetic changes in pancreatic cells after exposure to individual toxicants and their mixtures
(2020-12)
Pancreatic cancer has one of the worst fatality rates in oncology. Despite advances in treatment and recovery rates for other cancers, pancreatic cancer's lack of early symptomology culminates in a dismal five-year survival ...
Rigor and reproducibility of cancer medicine evidence
(2021-05)
The burden of cancer in the United States and abroad is comprised of significant morbidity, mortality, and psychological or financial harms. There remains a concern that the influence of published research is not maximized ...
Impact of female mate choice on pairing and pregnancy in prairie voles
(2021-12)
Female mate choice is one of the hallmark features of natural selection via sexual selection. This behavior is one of the key factors in determining what traits continue or diminish within a species. The prairie vole is a ...
β-funaltrexamine effects on lipopolysaccharide-induced behavior deficits and inflammation in mice
(2023-05)
Inflammation plays a pivotal role in neurological and peripheral disorders. Specifically, inflammation is one of the common factors in diseases such as anxiety, depression, Alzheimer’s disease (AD), Parkinson’s disease ...
Circadian rhythm evaluations to determine blood sample deposition time
(2020-05)
The use and applications of DNA and RNA analysis has become an invaluable forensic tool in criminal investigations. Recent research from this laboratory applied quantitative analysis of RNA as a means of estimating the age ...
Estrogen receptor-mediated modulation of inflammatory markers in hepatitis c virus pathogenesis
(2020-07)
Hepatitis C virus (HCV) is a global health concern whose pathogenesis depends largely on chronic inflammation; chronic infection with HCV is strongly linked to fibrosis/cirrhosis, liver failure, and hepatocellular carcinoma ...
Estrogen modulation of physiological body fluid control during repeated sodium deficiency
(2021-05)
Throughout much of life, women have lower blood pressures than men. However, after menopause, women's blood pressures surpass that of men, suggesting that estrogen plays a role in preventing hypertension. The low salt diet ...
Brain-derived neurotrophic factor (BDNF), B-catenin, and cortisol levels correlated with the severity of adverse childhood experiences (ACEs) score in patients with Schizophrenia spectrum disorders
(2021-05)
Psychosis, as seen in Schizophrenia and Schizoaffective disorder, is the most debilitating of psychiatric dysfunctions, affecting more than 21 million people per year globally.
Understanding the mechanism of nerve growth factor signaling during peripheral inflammation
(2020-07)
Scope and Method of Study: The purpose of this study is to understand the role of nerve growth factor (NGF) signaling in the development and maintenance of peripheral inflammation. Dermal-epidermal separation technique, ...