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Exploration of Lewis acidity and fluorophilicity of germanium compounds and their applications in C-F bond activation
(2021-07)
The elusive branched fluoro-oligogermane (Ph3Ge)3GeF which is the only crystallographically characterized Ge-F containing compound with unsupported Ge- Ge bonds, was successfully synthesized and its chemical/electrochemical ...
Greener and facile approaches towards synthesis of organic semiconducting materials
(2020-12)
Organic semiconductors (OSCs) are carbon-based materials that exhibit semiconducting properties and can be classified as π-conjugated small molecules and polymers. Over the past few decades, OSCs have attracted many fields ...
Catalytic N-arylation of triazoles and C-H activation leading to aromatic heterocycles
(2021-05)
5-Membered N-heterocycles have become valuable structural motives in organometallic chemistry, organic synthesis, and medicinal chemistry. Such compounds can act as ligands for organometallic complexes and catalysts, as ...
Palladium-catalyzed cyclization of drug candidates
(2020-05)
Ovarian cancer is both difficult to detect and difficult to treat, therefore the discovery of new therapies is important. Retinoids (retinoic acid derivatives) are known to induce cellular apoptosis in various cancers, ...
Syntheses of organic macromolecules via mechanochemistry and bioinspired antimicrobials
(2022-12)
Due to its biodegradable and biocompatible nature, polylactic acid (PLA) has found widespread use in biomedical applications. Controlled drug delivery using PLA-based nanoparticles (PLA-NPs) is an important tool for tuning ...
Overexpression, characterization, and structure-function studies of pheromone binding proteins from European corn borer, Ostrinia nubilalis
(2021-07)
Ostrinia nubilalis (European corn borer) has a huge impact on production of economically important crops in the USA and Europe. This species, similar to other lepidopterans, relies on olfaction to find their mating partners. ...
Novel syntheses and applications of layered transition metal hydroxides
(2022-07)
The dissertation herein reports the serendipitous discovery of hydrolysis reactions of later 3d transition metal acetates that deposit nanostructured thin films of corresponding layered metal hydroxides, M(OAc)2-x(OH)x·nH2O ...
Structure and functional characterization of the pheromone binding protein 2 from Ostrinia furnacalis
(2021-05)
Animal olfaction has an immense impact on their survival. The insect olfactory system is the most exquisitely sensitive in the animal kingdom. Moth antennae contain hair-like structures called sensilla, which are involved ...
Expression, purification, NMR structure, and molecular dynamics studies of Ost4 and Ost4V23D: A critical subunit of yeast oligosaccharyltransferase
(2021-05)
N-linked glycosylation is an essential and highly conserved protein modification reaction that takes place in all eukaryotes and some prokaryotes. This reaction is catalyzed by the enzyme complex, oligosaccharyltransferase ...
Development of metal oxide/metal carboxylate chemistry for the synthesis of metal tungstates, molybdates, and ferrites and extraction of iron from ores
(2022-05)
The research reported in this dissertation explored the application of the reactions between metal oxides and metal carboxylates for the synthesis of useful ternary metal oxides containing either molybdenum or tungsten, a ...