Browsing OSU Dissertations by Subject "parkinson's disease"
Now showing items 1-2 of 2
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Neuromelanin and alpha-synuclein modulation of inflammatory signaling in human astroglial cells
(2011-07)Scope and Method of Study: The scope of this dissertation was to study the effects of two Parkinson's disease associated molecules, neuromelanin and a-synuclein, on inflammatory signaling and expression in A172 astroglial ... -
Structural study of Parkinson's disease related protein LRRK2 and vaccinia virus protein A6
(2014-07)LRRK2 is a multi-domain protein expressed widely in organs. The mutations of LRRK2 are related to Parkinson's disease. The Roc domain in LRRK2 is a Ras GTPase, and its GTP hydrolysis activity has been proved to regulate ...