Browsing OSU Dissertations by Subject "desensitization"
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Modulation of AMPA receptor desensitization by nootropic drugs and endogenous proteins
(2005-05)AMPA receptors play a central role in basal excitatory synaptic transmission as well as synaptic maturation and plasticity. An important characteristic of AMPA receptors (AMPARs) is the rapid and profound desensitization ... -
Structure-function relationships of the pore-forming subunits of the AMPA receptor and the auxiliary subunit stargazin
(2009-07)AMPA receptors mediate the majority of neurotransmission in the CNS. One of the most important properties of AMPA receptors is their quick and profound desensitization in the presence of glutamate. Although, the mechanism ...