Browsing OSU Dissertations by Author "Xie, Aihua"
Now showing items 1-9 of 9
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Application of nuclear magnetic resonance to protein structure and protein-ligand interaction studies
Lin, Penghui (2015-07)NMR (Nuclear Magnetic Resonance) has been expanding its application since it was first discovered in the early 50s. In biophysics, it is a very powerful tool complement to X-ray crystallography for protein structure studies. ... -
Development and applications of infrared structural biology
Kang, Zhouyang (2014-05)Aspartic acid (Asp), Glutamic acid (Glu) and Tyrosine (Tyr) often play critical roles at the active sites of proteins. Probing the structural dynamics of functionally important Asp/Glu and Tyr provides crucial information ... -
Engineering metal parallel plate waveguides as a 2-D plane for high resolution THz time domain spectroscopy
Srikantaiah, Sree Harsha (2011-07)Scope and Method of Study: The research summarized in this dissertation is on the investigation of the application of metal parallel plate waveguides (PPWG) for performing high resolution spectroscopic measurements of ... -
Molecular dynamics study of protein mortalin and its mutants with anti-cancer agents flex hets
Bhandari, Dipendra (2021-07)Mortalin is a protein that belongs to a family of heat shock proteins (Hsp70) and has been found to be overexpressed in cancer cell lines. Mortalin has been found to interact with tumor suppressor protein p53, thus inhibiting ... -
Novel reactivity of silver isocyanide complexes and palladium bis(acyclic diaminocarbenes) as catalyst for the Nazarov cyclization
Miranda, Anthea Jacinta (2009-12)Scope and Method of Study: Inorganic Chemistry -
Probing hydrogen bonding interactions and proton transfer in proteins
Nie, Beining (2006-07)Scope and Method of Study: Hydrogen bonding is a fundamental element in protein structure and function. Breaking a single hydrogen bond may impair the stability of a protein. It is therefore important to probe dynamic ... -
Structural dynamics of photoactive yellow protein
Kaledhonkar, Sandip (2013-07)Photoactive yellow protein (PYP) is a blue light photoreceptor protein. PYP is a structural prototype of the PAS domain superfamily of regulating and signaling proteins. Upon absorption of a blue light photon, PYP exhibits ... -
Structure and dynamics studies of membrane and non-membrane proteins using NMR and MD simulations
Moktan Tamang, Hem Bahadur (2017-12)The protein structural knowledge is essential in defining molecular recognition rules that power the understanding of basic biological phenomenon. The structures of most proteins are determinable due to advancement in ... -
Structure-function relationships in the photoactive yellow protein family of photoreceptors
Rathod, Rachana Ramila Suresh (2014-12)The amino acid sequence of a protein determines its three-dimensional structure, which in turn determines its functional properties. An intensively studied but still partially unresolved question is how the structure of a ...