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Probing hydrogen bonding interactions and proton transfer in proteins
(2006-07)
Scope and Method of Study: Hydrogen bonding is a fundamental element in protein structure and function. Breaking a single hydrogen bond may impair the stability of a protein. It is therefore important to probe dynamic ...
Development and applications of infrared structural biology
(2014-05)
Aspartic acid (Asp), Glutamic acid (Glu) and Tyrosine (Tyr) often play critical roles at the active sites of proteins. Probing the structural dynamics of functionally important Asp/Glu and Tyr provides crucial information ...