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Apoptotic and bioenergetic changes in pancreatic cells after exposure to individual toxicants and their mixtures
(2020-12)
Pancreatic cancer has one of the worst fatality rates in oncology. Despite advances in treatment and recovery rates for other cancers, pancreatic cancer's lack of early symptomology culminates in a dismal five-year survival ...
Rigor and reproducibility of cancer medicine evidence
(2021-05)
The burden of cancer in the United States and abroad is comprised of significant morbidity, mortality, and psychological or financial harms. There remains a concern that the influence of published research is not maximized ...
Relationship of Parental Overprotection, Child Vulnerabililty, and Parenting Stress to Emotional, Behavioral, and Social Adjustment in Children Diagnosed with Cancer
(Oklahoma State University, 2005-12-01)
This study examined the relationship of parental overprotection, perceived child vulnerability, and parenting stress to parent-reported emotional, behavioral, and social functioning in children with cancer. Parenting stress ...
Social relationships and health-related behavior in adolescents with cancer
(2007-07)
Scope and Method of Study: The purpose of the current study was to provide an examination of how dimensions of close peer and dating relationships (i.e., social support, negative interactions, dating anxiety, fear of ...
Impact of ferroptosis induction on iron metabolism in cancer cells harboring TP53 mutations
(2020-12)
The tumor suppressor gene TP53 is the most commonly mutated gene in human cancer, but mutations in TP53 do not just result in loss of tumor suppressor function, they can also promote cancer progression by altering cellular ...
Development of Targeted Liposomal Formulation Approaches for Enhanced Colorectal Cancer Therapy
(2019-05)
Colorectal cancer (CRC) is the 4th most commonly detected cancer in the USA. Despite promising advances, the 5-year survival rate for the metastatic disease remains dismal (<15%) due to the presence of chemo-resistant and ...
Influence of HDAC inhibition on the maintanance of iron homeostasis and the acquisition of oncogenic phenotype in cancer cells
(2021-12)
Epithelial-to-mesenchymal transition (EMT), an essential mechanism for development and wound healing, but in cancer it also mediates the progression and spread of aggressive tumors while increasing therapeutic resistance. ...
Relationship of cortisol to psychological adjustment in parents of children diagnosed with cancer
(2012-07)
Scope and Method of Study: The current study examined the relation of physiological stress as measured by salivary cortisol in a sample of parents of children who had been diagnosed and receiving treatment for pediatric ...