Search
Now showing items 41-50 of 62
Characterization of functional domains of Saccharomyces cerevisiae septins
(2005-05)
S. cerevisiae expresses 5 septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p and Shs1p) during mitotic growth. Septins interact with each other, colocalize to the cortex at the mother-bud neck, and are required for the localization ...
Characterization and functional analysis of extensins and LRR-extensin in cotton
(2004-12)
Scope and Method of Study: This research involved the characterization and functional analysis of two extensins (extensins # 2 and # 3), and an LRR-extensin (# 65631). 5' RACE experiment was done to determine the 5' ends ...
Proteomics fingerprints of AUY922 and 17-DMAG indicate common mechanisms of action for Hsp90 inhibitors
(2013-12)
In this work, we identified the proteomics fingerprint of the anti-cancer drug candidate AUY922 in Jurkat leukemia cells and compared AUY922's fingerprint to the proteomics fingerprints of flagship Hsp90 inhibitors 17-DMAG ...
Glycolysis and glyceroneogenesis in adipocytes: Effects of rosiglitazone, an anti-diabetic drug
(2010-07)
Findings and Conclusions:
Identification and characterization of natural compound inhibitors of the Hsp90 chaperone complex
(2013-07)
The 90 kDa Heat Shock Protein (Hsp90) has emerged as a major therapeutic target for a number of diseases, the most notable of which is cancer. Accordingly, many groups are attempting to develop small molecules that modulate ...
RNA-seq assisted gene modeling and annotation, transcriptome study and functional analysis of stress responsive peptides of Manduca sexta
(2016-12)
Manduca sexta is a widely used model insect. The genome sequence was determined using 454 sequencing technology, and Official Gene Set (OGS) 2.0 was generated with help from RNA-seq data and manually annotation by researchers ...
Functional modulation of DBC2 by the Hsp90 chaperone machine
(2012-05)
Scope and Method of Study: This study involved looking at various mechanistic associations of the tumor suppressor DBC2 with the Hsp90 chaperone machine. Along with aspects of functional relationships of co-chaperone and ...