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Characterization and quantification of necrotic tissues and morphology in multicellular ovarian cancer tumor spheroids using optical coherence tomography
(2021-05-13)
The three-dimensional (3D) tumor spheroid model is a critical tool for high-throughput ovarian cancer research and anticancer drug development in vitro. However, the 3D structure prevents high-resolution imaging of the ...
Peptide Aggregation Induced Immunogenic Cell Death
(2022-12-16)
Cell death is an inevitable biological outcome, every living thing dies. However, how cells die is an important question and ultimately is decisive in homeostasis and disease progression. Immune system is in the center of ...
Natural and Synthetic Biomaterials for Engineering Multicellular Tumor Spheroids
(2020-10-28)
The lack of in vitro models that represent the native tumor microenvironment is a significant challenge for cancer research. Two-dimensional (2D) monolayer culture has long been the standard for in vitro cell-based studies. ...