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FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia
(PLos One, 2015-09-22)
Background Friedreich ataxia is caused by an expanded GAA triplet-repeat sequence in intron 1 of the FXN gene that results in epigenetic silencing of the FXN promoter. This silencing mechanism is seen in patient-derived ...
Controllability of Linear and Nonlinear Control Systems related through Simulation Relations
(2015-12)
For nonlinear input-disturbance systems that are connected by a simulation relation, we examine to what extent they share certain controllability properties. Specifically our main objective is to determine the conditions ...
A Pectate Lyase-Coding Gene Abundantly Expressed during Early Stages of Infection Is Required for Full Virulence in Alternaria brassicicola
(PLos One, 2015-05-21)
Alternaria brassicicola causes black spot disease of Brassica species. The functional importance of pectin digestion enzymes and unidentified phytotoxins in fungal pathogenesis has been suspected but not verified in A. ...
Much to Lose by Revolution: Nothing to Dread from Reform: Education Reform as a Means of Class Alliance in Victorian England Undergraduate
(2015-04-01)
Many historians agree that the Victorian period was crucial in the development of education in England. In fact Dinah Birch, in her 2008 book Our Victorian Education goes so far as to say that it was the genesis of the ...
REDUCTION OF ASYMMETRICAL COMPETITION THROUGH COGNITIVE ADAPTATIONS IN TWO SYMPATRIC CHIPMUNKS
(2015-08)
Asymmetrical competition occurs frequently and can potentially lead to a small species facing resource exclusion. When this competition occurs for food resources, smaller species often have to compensate for this pressure ...
The representations of p-adic fields associated to elliptic curves
(2015)
The goal of this dissertation is to find the irreducible, admissible representation
of GL(2; F) attached to an elliptic curve E over a p-adic field F. Associated
to E is a 2-dimensional complex representation of the ...
Our squirrels will have elephant ears : indigenous perspectives on climate change in the south central United States
(2015)
As climate change impacts areas around the world Indigenous communities are being impacted disproportionately. In the US a number of tribes are in differing levels of response and adaptation. In the south central U.S. there ...