Browsing The University of Oklahoma by Author "Yan Dai"
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Novel Inducers of Fetal Globin Identified through High Throughput Screening (HTS) Are Active In Vivo in Anemic Baboons and Transgenic Mice
Michael S. Boosalis; Jose I. Sangerman; Gary L. White; Roman F. Wolf; Ling Shen; Yan Dai; Emily White; Levi H. Makala; Biaoru Li; Betty S. Pace; Mehdi Nouraie; Douglas V. Faller; Susan P. Perrine (PLos One, 2015-12-29)High-level fetal (γ) globin expression ameliorates clinical severity of the beta (β) hemoglobinopathies, and safe, orally-bioavailable γ-globin inducing agents would benefit many patients. We adapted a LCR-γ-globin ...