Browsing by Subject "innate immunity"
Now showing items 1-9 of 9
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Characterization of recombinant B. abortus strain RB51SOD toward understanding the uncorrelated innate and adaptive immune responses induced by RB51SOD compared to its parent vaccine strain RB51
(Frontiers Media, 2011-11-25)Brucella abortus is a Gram-negative, facultative intracellular pathogen for several mammals, including humans. Live attenuated B. abortus strain RB51 is currently the official vaccine used against bovine brucellosis in the ... -
Characterization of the in vitro immune function of reptile macrophages from Sceloporus occidentalis
(2008-07)Scope and Method of Study: In vitro study of cellular immune function -
Chicken Cathelicidins: Tissue Expression, Developmental Regulation, and Mass Spectrometric Quantification
(Oklahoma State University, 2010-07-01)The purposes of the study are to determine the tissue and developmental expressions of chicken cathelicidins and to develop a mass spectrometric assay for quantification of chicken cathelicidins. RNA was isolated from a ... -
Comprehensive Analysis of the Manduca Sexta Immunotranscriptome
(Oklahoma State University, 2012-05-01)As a biochemical model, Manduca sexta substantially contributed to our knowledge on insect innate immunity. The RNA-Seq approach based on massively parallel pyrosequencing was implemented in three studies to examine tissue ... -
Epigenetic modulation of avian host defense peptide synthesis
(Oklahoma State University, 2020-04-24)The threat of antibiotic resistance has catalyzed the demand for novel antibiotic alternatives in veterinary and human medicine. In response, the activation of the innate immune system has become a promising alternative ... -
Interaction of the tick immune system with transmitted pathogens
(Frontiers Media, 2013-07-16)Ticks are hematophagous arachnids transmitting a wide variety of pathogens including viruses, bacteria, and protozoans to their vertebrate hosts. The tick vector competence has to be intimately linked to the ability of ... -
Mycobacteria, metals, and the macrophage
(Wiley, 2015-03)Mycobacterium tuberculosis is a facultative intracellular pathogen that thrives inside host macrophages. A key trait of M. tuberculosis is to exploit and manipulate metal cation trafficking inside infected macrophages to ... -
Structure of a prophenoloxidase (PPO) from Anopheles gambiae provides new insights into the mechanism of PPO activation
(BioMed Central, 2016-01-05)Background: Phenoloxidase (PO)-catalyzed melanization is a universal defense mechanism of insects against pathogenic and parasitic infections. In mosquitos such as Anopheles gambiae, melanotic encapsulation is a resistance ... -
Tissue expression of claudin-1 and claudin-2 tight junction proteins in chickens
(2016-04-15)Understanding gut homeostasis is an active area of research in livestock animals, as it is key to improving animal health and efficiency. Tight junction proteins are responsible for preventing the transport of foreign ...