Browsing by Subject "inflammation"
Now showing items 1-17 of 17
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Acute effects of social defeat on neuroinflammatory signaling in mice
(Oklahoma State University Center for Health Services, 2020-02-28)Background: Psychosocial stress negatively affects both physical and mental health; and stress-related psychiatric disorders are more common in women. Interestingly, preclinical studies have predominately studied the effects ... -
Anti-Inflammatory Properties of Oklahoma Grapes
(Oklahoma State University, 2010-05-01)Many debilitating chronic conditions are linked to chronic inflammation. Recent studies have indicated that a relationship exists between phenolic compounds found in grapes and the reduction of chronic inflammation. The ... -
Characterization of Cell-free Dna in the Bloodstream of Normal Individuals and Those with Inflammation
(Oklahoma State University, 2012-07-01)The presence of DNA in the plasma of humans has been known since 1948. The pathway that leads to the liberation of DNA from the cell still remains open to debate. . Scientists have proposed the following mechanisms underlying ... -
Developmental signaling and acute lung injury
(2014-05)The present study is initiated to explore the potential implication of developmental signaling in AEC I injury, acute inflammatory response, and host defense against pathogen invasion during the pathogenesis of ALI/ARDS. -
Effect of whole foods on the gut-adipose axis in models of diet-induced obesity: The case of wheat germ and pinto beans
(2019-12)The global alteration in food supply characterized by increased western-style diets (high in saturated fat and refined sugar) is a major driver of the obesity epidemic. Western diets disrupt the host-gut bacteria homeostasis, ... -
Effects of Ashwagandha on delayed onset muscle soreness
(2021-07)Delayed onset muscle soreness (DOMS), is a phenomenon that typically occurs within 8-48 hours, and can peak within 24-72 hours after a bout of intense resistance training[1]. To combat this pain, analgesics such as ... -
Effects of Blueberry Supplementation and Dietary Flavonoid Intakes on Antioxidant Status and Inflammation
(Oklahoma State University, 2011-07-01)The objective of our study was to investigate the effects of blueberry flavonoids on inflammation and antioxidant status in subjects identified with Metabolic Syndrome. Nineteen subjects identified with metabolic syndrome ... -
Effects of Digitaria exilis (Fonio) on inflammation and diabetes pathogenesis
(2011-07)Scope and Method of Study: Digitaria exilis (fonio), a wild cereal consumed in West Africa, is rich in chromium, B-glucans and sulfur amino acids, factors known to modulate inflammation and diabetes. However the mechanisms ... -
Effects of Pomegranate Polyphenol Supplementation on Biomarkers of Oxidative Stress and Inflammation in Adults With Type 2 Diabetes Versus Healthy Controls
(Oklahoma State University, 2010-07-01)Pomegranates have significant anti-atherosclerotic, anti-hypertensive, anti-oxidative, and anti-inflammatory effects. We tested the hypothesis that pomegranate polyphenols will not affect fasting blood glucose, insulin, ... -
Effects of wheat germ supplementation on inflammation, metabolic, and gut health markers in overweight adults
(2021-07)Objectives: Overweight and obesity is linked to several metabolic disturbances including type 2 diabetes. Functional foods such as wheat germ (WG) have been shown to improve metabolic markers in animals and humans alike. ... -
Genistein Reduces Production of Proinflammatory Molecules in Human Chondrocytes
(Oklahoma State University, 2006-05-01)Previously, we reported that cartilage is an estrogen receptor (ER) positive tissue and that mRNA levels of ER increase in postmenopausal women with osteoarthritis. Based on our findings and those of other investigators, ... -
Has Genetic Improvement of Wheat Resulted in Negative Effects on Gut Health?
(2019-07)Objectives: Wheat consumption has recently declined amid growing concerns about gluten-sensitivity. To determine if genetic manipulation of wheat contributes to gut inflammation, we investigated the effects of modern and ... -
Metabolic Risk Factors for Cardiovascular Disease in Oklahoma Adults with Abdominal Adiposity and Dyslipidemia : a Cross-Sectional Study.
(Oklahoma State University, 2013-12-01)Dietary intakes of fruits and vegetables have been shown to lower risks of cardiovascular complications in both epidemiological and clinical studies. In particular, the polyphenol subclass of flavonoids has been found to ... -
Metabolic Risk Factors for Cardiovascular Disease in Oklahoma Adults with Abdominal Adiposity and Dyslipidemia: a Cross-sectional Study.
(Oklahoma State University, 2013-12-01)Dietary intakes of fruits and vegetables have been shown to lower risks of cardiovascular complications in both epidemiological and clinical studies. In particular, the polyphenol subclass of flavonoids has been found to ... -
Protective effects of β-Funaltrexamine against LPS-induced CCL2 expression and behavioral deficits
(Oklahoma State University Center for Health Sciences, 2023-02-17)Background: Inflammation is present in both neurological and peripheral disorders. Specifically, inflammation is one of the common factors in diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), mood disorders ... -
Ulcerative colitis: The MeCP2/H3K4me3 interaction in the hypermethylated promoter modulates NGF gene expression
(Oklahoma State University Center for Health Sciences, 2023-02-17)Background: Ulcerative colitis (UC) is associated with symptoms like abdominal pain, diarrhea, fatigue, reduced appetite, and weight loss. According to CDC, approx. 1 million Americans are reportedly diagnosed with UC every ... -
Understanding the mechanism of nerve growth factor signaling during peripheral inflammation
(2020-07)Scope and Method of Study: The purpose of this study is to understand the role of nerve growth factor (NGF) signaling in the development and maintenance of peripheral inflammation. Dermal-epidermal separation technique, ...