Now showing items 1-2 of 2

    • Evidence for alternative quaternary structure in a bacterial Type III secretion system chaperone 

      Barta, Michael L.; Zhang, Lingling; Picking, Wendy L.; Geisbrecht, Brian V. (BioMed Central, 2010-07-15)
      Background: Type III secretion systems are a common virulence mechanism in many Gram-negative bacterial pathogens. These systems use a nanomachine resembling a molecular needle and syringe to provide an energized conduit ...
    • Heme and hemoglobin utilization by Mycobacterium tuberculosis 

      Mitra, Avishek; Ko, Ying-Hui; Cingolani, Gino; Niederweis, Michael (Springer Nature, 2019-09-18)
      Iron is essential for growth of Mycobacterium tuberculosis (Mtb), but most iron in the human body is stored in heme within hemoglobin. Here, we demonstrate that the substrate-binding protein DppA of the inner membrane Dpp ...