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    • Hyperinsulinemia down-regulates TLR4 expression in the mammalian heart 

      de Laat, Melody A.; Gruntmeir, Kaylynn J.; Pollitt, Christopher C.; McGowan, Catherine M.; Sillence, Martin N.; Lacombe, Veronique A. (Frontiers Media, 2014-07-22)
      Toll-like receptors (TLR) are key regulators of innate immune and inflammatory responses and their activation is linked to impaired glucose metabolism during metabolic disease. Determination of whether TLR4 signaling can ...