Browsing by Subject "cell death"
Now showing items 1-3 of 3
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Coxiella burnetii Nine Mile II proteins modulate gene expression of monocytic host cells during infection
(BioMed Central, 2010-09-20)Background: Coxiella burnetii is an intracellular bacterial pathogen that causes acute and chronic disease in humans. Bacterial replication occurs within enlarged parasitophorous vacuoles (PV) of eukaryotic cells, the ... -
Developmental signaling and acute lung injury
(2014-05)The present study is initiated to explore the potential implication of developmental signaling in AEC I injury, acute inflammatory response, and host defense against pathogen invasion during the pathogenesis of ALI/ARDS. -
Wnt3a mitigates acute lung injury by reducing P2X7 receptor-mediated alveolar epithelial type I cell death
(Nature Publishing Group, 2014-06-12)Acute lung injury (ALI) is characterized by pulmonary endothelial and epithelial cell damage, and loss of the alveolar-capillary barrier. We have previously shown that P2X7 receptor (P2X7R), a cell death receptor, is ...