Browsing by Subject "Nervous system Degeneration."
Now showing items 1-2 of 2
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Investigation into the in vivo metabolism of glutathionyl conjugates of dopamine and norepinephrine: Possible insights into neurodegenerative diseases.
(1997)The in vitro and in vivo hydrolyses of 5-S-Glu-NE were investigated in rat brain homogenates and by intracerebroventricular (icv) administration in rat brains. Under in vitro conditions, 5-S-Glu-NE was hydrolyzed to give ... -
Investigations into the neurodegenerative mode of action of dihydroxytetrahydroquinoline derivatives.
(1997)Preliminary testing of a dihydroxyguinoline derivative, 3-amino-6,7-dihydroxy-1,2,3,4-tetrahydroquinoline (6,7-ADTQ), showed substantial serotonergic depletion in mouse whole brain, but with only moderate selectivity. This ...