Browsing by Subject "Chemistry, Biochemistry."
Now showing items 1-20 of 171
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An analysis of the activation of the adipogenic differentiation pathway in the bone marrow stroma by members of the nuclear hormone receptor family.
(1997)The bone marrow stroma is composed of a diverse array of cell types that have unique functions. Of the different types, the adipocyte is the most abundant. It is not clear what purpose adipocytes serve in the bone marrow. ... -
BACTERIOPHAGE NANOFIBERS ENABLED NANOSTRUCTURES AND TARGET-RECOGNITION FOR BIO-APPLICATIONS
(2015)Nanostructure is an object system that has dimensions on the nanoscale, i.e. between 0.1 and 100 nanometers. It includes nanotextured surface, nanotube, nanorod, nanofilament, nanoparticle, etc. The field of nanostructure ... -
Binding and transport through ferric siderophore receptors, FepA and FhuA.
(2006)Under iron deficient conditions, Gram-negative bacteria like E. coli secrete siderophores to chelate iron in the extracellular medium. Ligand-gated porins (LGPs) transport the ferric siderophore complexes across the outer ... -
THE BIOCHEMICAL CHARACTERIZATION OF TWO PHOSPHORELAY SIGNALING PROTEINS: YPD1 HOMOLOGS FROM SACCHAROMYCES CEREVISIAE AND CRYPTOCOCCUS NEOFORMANS
(2016-08)Histidine-to-aspartate multi-step phosphorelay systems are used extensively by eukaryotes and bacteria to sense and respond to changes in their external environment and to control the regulation of crucial biological ... -
Biochemical studies of lysosomal enzymes in experimental muscular dystrophy /
(The University of Oklahoma., 1964) -
A bioinorganic approach to the study of the interactions of nitrogen oxides with manganese porphyrins and manganese- and cobalt-reconstituted myoglobin.
(2007)This dissertation deals with the interaction of the biologically important nitrogen oxides (nitric oxide and nitrite) with manganese and ruthenium centers in small inorganic porphyrin and nonporphyrin complexes as well as ... -
BIONANOFIBER-BASED NANOSTRUCTURE FABRICATION AND APPLICATIONS
(2017-12)Among various strategies for the synthesis and assembly of nano-scaled structures, bio-templating is an efficient method due to the unique physical and chemical properties of the template bionanomaterials, thus has experienced ... -
Characterization of a Sporulation Related Two-Component Signaling System in Clostridioides difficile
(2023-12-15)Clostridioides difficile is a spore-forming anaerobic human pathogen, that is commonly associated with antibiotic therapy in adults. The disturbance of the gut microbiota, typically caused by antibiotics, allows for an ... -
Characterization of the biochemical and biophysical mechanisms fundamental to receptor-mediated white blood cell accumulation.
(1998)The recruitment of circulating leukocytes to areas of infection and injury is an important aspect of the immune response process. Leukocytes initially attach to and roll on the activated endothelial cells lining the blood ... -
Characterization of the protein-protein interactions of the type-II toxin-antitoxin system ParDE1 from Pseudomonas aeruginosa
(2023-05-12)The emergence of multidrug-resistant bacteria has led to an ever-growing antibiotic resistance crisis. To combat this growing crisis, new strategies for controlling bacterial cell growth must be developed. An underdeveloped ... -
Characterization of the second-half reaction of O-acetylserine sulfhydrylase-A and the reaction of O-acetylserine sulfhydrylase-B from Salmonella typhimurium.
(2004)The O-acetylserine sulfhydrylase-B (OASS-B) was recently overexpressed and purified to electrophoretic homogeneity (>98% pure). Both the quantity and purity of the enzyme permit more kinetic and structurally based studies ... -
Chemical Genetics and Molecular Pharmacology of the Oxysterol-Binding Proteins
(2020-07)Oxysterol-binding protein (OSBP) and the OSBP-related proteins (ORPs) comprise a family of lipid-binding proteins organized into 6 subfamilies in humans. ORP subfamily 1 consists of OSBP and its closest homolog, ORP4. OSBP ... -
Chemical reactivation of Escherichia coli B from radiation damage /
(The University of Oklahoma., 1969) -
Chemical studies of bovine transferrin /
(The University of Oklahoma., 1968)