Browsing by Subject "Antibacterial design"
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Development of synthetic methodologies for N- to C-terminal cyclization of peptidomimetic small molecules and in silico and in vitro studies of the role of cyclization on antibacterial and antiviral activities
(2022-05-13)Among the different mechanisms of resistance in Gram-negative bacteria, the permeability barrier of the outer membrane and efflux pumps represent a significant challenge to address as they synergize to reduce accumulation ...