Now showing items 1-4 of 4

    • Enzymatic assessment of cells with distinct TP53 mutations 

      Kouplen, Kate; Hermann, Evan (Oklahoma State University, 2021-10-09)
      The p53 transcription factor, encoded by the human gene TP53, is the most commonly mutated gene in human cancers. Once the TP53 gene is mutated, p53 proteins not only lose their tumor suppression abilities but can also ...
    • Enzymatic assessment of cells with distinct TP53 mutations 

      Kouplen, Kate (2022-04-19)
      The P53 transcription factor, encoded by the human gene TP53, is the most commonly mutated gene in human cancers. The P53 transcription factor suppresses tumor growth through the regulation of genes with diverse biological ...
    • Enzymatic assessment of cells with distinct TP53 mutations 

      Kouplen, Kate; Hermann, Evan; Cardona, Cameron (Oklahoma State University, 2022-04-15)
      The p53 transcription factor, encoded by the human gene TP53, is the most commonly mutated gene in human cancers. Once the TP53 gene is mutated, p53 proteins not only lose their tumor suppression abilities but can also ...
    • Impact of ferroptosis induction on iron metabolism in cancer cells harboring TP53 mutations 

      Thompson, Laurie Renee (2020-12)
      The tumor suppressor gene TP53 is the most commonly mutated gene in human cancer, but mutations in TP53 do not just result in loss of tumor suppressor function, they can also promote cancer progression by altering cellular ...