Now showing items 1-2 of 2

    • Nano-ablative immunotherapy for cancer treatment 

      Hoover, Ashley R.; Liu, Kaili; Valerio, Trisha I.; Mukherjee, Priyabrata; Chen, Wei R. (2021-08-11)
      Immunotherapy has provided a new avenue to treat metastatic cancers, which result in ∼90% of cancer related deaths. However, current immunotherapies, such as immune checkpoint therapy (ICT), have met with limited success, ...
    • Single-cell RNA sequencing reveals localized tumourablation and intratumoural immunostimulant deliverypotentiate T cell mediated tumour killing 

      Hoover, Ashley R.; Liu, Kaili; DeVette, Christa I.; Krawic, Jason R.; Medcalf, Alexandra D.; West, Connor L.; Hode, Tomas; Lam, Samuel S.K.; Welm, Alana L.; Sun, Xiao-Hong; Hildebrand, William H.; Chen, Wei R. (2022-06-05)
      Background: Metastatic breast cancer poses great challenge in cancer treatment. N-dihydrogalactochitosan (GC) is a novel immunoadjuvant that stimulates systemic immune responses when administered intratumourally following ...