Browsing by Author "Li, Shitao"
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High throughput assay for screening host restriction factors and antivirals targeting Influenza A virus
Wang, Lingyan; Li, Wenjun; Li, Shitao (Frontiers Media, 2016-06-03)Influenza A virus (IAV) is a human respiratory pathogen that causes seasonal epidemics and occasional global pandemics with devastating levels of morbidity and mortality. Currently approved treatments against influenza are ... -
Influenza A virus-host protein interactions control viral pathogenesis
Zhao, Mengmeng; Wang, Lingyan; Li, Shitao (MDPI, 2017-08-01)The influenza A virus (IAV), a member of the Orthomyxoviridae family, is a highly transmissible respiratory pathogen and represents a continued threat to global health with considerable economic and social impact. IAV is ... -
Neutrophil characterization for the development of novel combination therapy in a murine model of influenza pneumonia with secondary pneumococcal coinfection
Rudd, Jennifer (2018-05)Pneumococcal coinfection is a critical complication of influenza pneumonia and has played a vital role in the lethal synergism seen in influenza pandemics throughout the last century. This project focuses on identifying ... -
Role of TRIM41 in antiviral defense against influenza and vesicular stomatitis virus
Patil, Girish Nandkumar (2020-05)TRIM41 is a member of TRIM family of host proteins. TRIM proteins are E3 ubiquitin ligase proteins and play important roles in various cellular functions like tumorigenesis, autophagy, innate, and intrinsic antiviral ...