Browsing by Author "Koehler, Gerwald"
Now showing items 1-15 of 15
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Apoptotic and bioenergetic changes in pancreatic cells after exposure to individual toxicants and their mixtures
Schweitzer, Amie R. (2020-12)Pancreatic cancer has one of the worst fatality rates in oncology. Despite advances in treatment and recovery rates for other cancers, pancreatic cancer's lack of early symptomology culminates in a dismal five-year survival ... -
Archaea in mammalian gut microbiomes
Dange, Shilpa; Torres, Alejandro; Assefa, Senait; Rivera, Steven; Richardson, Thomas; Perez, Brenda; Vazquez-Sanroman, Dolores; Koehler, Gerwald (Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Archaea are the most enigmatic domain of the three domains of life. Archaea are unique in that they share some characteristics with bacteria and others with eukaryotes while they are also distinct from these ... -
Archaea in mammalian gut microbiomes
Dange, Shilpa (2023-05)Archaea are the most enigmatic of the three domains of life. Most archaea are extremophiles found in highly acidic, high-salt, or high-temperature environments. However, members of the archaea also have been discovered in ... -
Circadian rhythm evaluations to determine blood sample deposition time
Kirk, Dianne E. (2020-05)The use and applications of DNA and RNA analysis has become an invaluable forensic tool in criminal investigations. Recent research from this laboratory applied quantitative analysis of RNA as a means of estimating the age ... -
Detection of RNA methylation patterns in forensically relevant transcripts in dried bloodstains
Lohr, Chaelynne (2022-07)RNA degradation kinetics can be used to estimate the age of a biological sample found at a crime scene. RNA sequencing of transcripts from various tissue types shows that degradation occurs faster at the 5’ end than the ... -
Evaluation of Collection Methods for Extraction of Trace Amounts of DNA from Cloth Substrates
Burgei, Kaitlyn Susanna (2015-07-01)DNA analysis has become the golden standard in many crime laboratories around the world. As technology advances, new possibilities arise in using evidence left at crime scenes, touch DNA being one of these possibilities. ... -
Impact of female mate choice on pairing and pregnancy in prairie voles
Francis, Amie (2021-12)Female mate choice is one of the hallmark features of natural selection via sexual selection. This behavior is one of the key factors in determining what traits continue or diminish within a species. The prairie vole is a ... -
Investigation of Genotype/chemotype Correlations in Cannabis Sativa
Allen, Lindsey Nicole (2015-12-01)Though Cannabis sativa has been used as a medical treatment for centuries, recent American political controversy surrounding the legalization of marijuana has generated interest into the mechanism of cannabinoid biosynthesis. ... -
New age: Quantitative morphometry for the 21st century - Advances in the study of dorsal root ganglion neurons
Anderson, Michael Brian (2021-12)Dorsal root ganglion (DRG) neurons transduce sensory information in peripheral tissues, transmitting centrally as action potential frequency, along second and third order neurons for processing in the somatosensory cortex. ... -
Next-Generation Genome Sequencing of Lactobacilli
Bigelow, Simone F. (2015-05-01)The gastrointestinal microbiome plays a critical role in aiding the host in maintaining homeostasis. Probiotic bacteria can aid the microbiota in maintenance of homeostasis by performing a multitude of functions such as ... -
Pain and perspective: Compartmented co-culture to evaluate sensory neuron peripheral glutamate receptors
Myers, Warren Kellen (2016-07)The neurotransmitter L-Glutamate is the primary excitatory neurotransmitter of sensory neurons in the dorsal root ganglion (DRG). These neurons may also express ionotropic glutamate receptors, causing the potential for ... -
Patterns of Degradation in Prm1 and Semg1 Transcripts in Semen During 6 Months of Aging
Sherier, Allison J. (2016-07-01)The purpose of this study was to study the degradation rates of mRNA molecules in semen stains as a possible approach to estimating the age of semen samples found at crime scenes. Specific primers directing amplicons of ... -
Phenotypic characterization of environmental Clostridioides difficile isolates from wastewater and seafood in Taiwan
Moulis, Gianna (2022-07)Clostridioides difficile (C. difficile) is a gram-positive, toxin-producing, spore-forming anaerobe, and leading cause of nosocomial antibiotic-associated diarrhea (AAD). C. difficile is present worldwide and the disease ... -
Transference of Methicillin Resistance in Staphylococcus Aureus Using Antibiotic Challenge
Pham, Trang Xuan (Oklahoma State University, 2011-12-01)The specific aim of this study was to document the transfer of a functional methicillin resistance gene, mecA , from methicillin resistant Staphylococcus aureus (MRSA) genomic DNA to methicillin sensitive Staphylococcal ... -
β-funaltrexamine effects on lipopolysaccharide-induced behavior deficits and inflammation in mice
Myers, Stephanie (2023-05)Inflammation plays a pivotal role in neurological and peripheral disorders. Specifically, inflammation is one of the common factors in diseases such as anxiety, depression, Alzheimer’s disease (AD), Parkinson’s disease ...