Browsing by Author "Cook, Gabriel A."
Now showing items 1-8 of 8
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Effects of glycosylation on y-Sarcoglycan
Gardner, Allye (2019-04-26)Glycoproteins are the underappreciated stars in the world of science. These proteins – specifically, membrane-bound glycoproteins – are known to have been difficult to study, for they present many hurdles: they are complex, ... -
Expression and characterization of the membrane proteins tcr alpha WT and gamma-sarcolgycan with the quantification of in vitro glycosylated gamma-sarcoglycan
Harris, Michael Shaun (2022-05)Membrane proteins are a continually growing area of research in science as they are prevalent in a multitude of different disease states in humans. Membrane proteins are responsible for different biological processes in ... -
Expression and isolation of the membrane proteoglycan syndecan-1 from E. coli
McIntire, Ryan (2019-04-26)Syndecan-1 is a membrane proteoglycan, which is a protein with glycosaminoglycans, or long carbohydrate chains, attached to its extracellular domain. The syndecan family is composed of various proteoglycans that each aid ... -
Expression and isolation of the membrane proteoglycan syndecan-1 from E. coli
McIntire, Ryan Scott; Cook, Gabriel A. (Oklahoma State University, 2019-04-26)Syndecan-1 is a membrane proteoglycan, which is a protein with glycosaminoglycans, or long carbohydrate chains, attached to its extracellular domain. The syndecan family is composed of various proteoglycans that each aid ... -
Expression, characterization, and in vitro glycosylation of ectodomains from the membrane protein syndecan-1
Anderson, Austin Ray (2022-12)Membrane proteins are a key component of numerous biological processes such as signal transduction, transportation, and various cell-cell interactions. Nearly one-third of all genes encode for membrane proteins and around ... -
Greener and facile approaches towards synthesis of organic semiconducting materials
Pary, Fathima Fazna (2020-12)Organic semiconductors (OSCs) are carbon-based materials that exhibit semiconducting properties and can be classified as π-conjugated small molecules and polymers. Over the past few decades, OSCs have attracted many fields ... -
NMR studies of membrane proteins
Cook, Gabriel A.; Opella, Stanley J. (Springer Nature, 2010-01-01)Nuclear magnetic resonance studies of membrane proteins yield valuable insights into their structure and topology. For example, the tilt angle and rotation of the helices in an ion channel can be determined by solid-state ... -
Using lipid nanodiscs for the in vitro glycosylation of membrane proteins
Dolan, Rachel F. (Oklahoma State University, 2022-04-19)Membrane proteins are involved in a number of human diseases are important to study. Due to the fact that these proteins are, by nature, insoluble in aqueous solutions, they require detergent or lipid environments that ...