Browsing by Author "Cabezas-Cruz, Alejandro"

Now showing items 1-5 of 5

    • Anaplasma phagocytophilum infection subverts carbohydrate metabolic pathways in the tick vector, Ixodes scapularis 

      Cabezas-Cruz, Alejandro; Alberdi, Pilar; Valdes, James J.; Villar, Margarita; Fuente, Jose de la (Frontiers Media, 2017-02-07)
      The obligate intracellular pathogen, Anaplasma phagocytophilum, is the causative agent of human, equine, and canine granulocytic anaplasmosis and tick-borne fever (TBF) in ruminants. A. phagocytophilum has become an emerging ...

    • Anaplasma phagocytophilum MSP4 and HSP70 proteins are involved in interactions with host cells during pathogen infection 

      Contreras, Marinela; Alberdi, Pilar; Mateos-Hernandez, Lourdes; Fernandez de Mera, Isabel G.; Garcia-Perez, Ana L.; Vancova, Marie; Villar, Margarita; Ayllon, Nieves; Cabezas-Cruz, Alejandro; Valdes, James J.; Stuen, Snorre; Gortazar, Christian; de la Fuente, Jose (Frontiers Media, 2017-07-05)
      Anaplasma phagocytophilum transmembrane and surface proteins play a role during infection and multiplication in host neutrophils and tick vector cells. Recently, A. phagocytophilum Major surface protein 4 (MSP4) and Heat ...

    • Effect of blood type on anti-a-Gal immunity and the incidence of infectious diseases 

      Cabezas-Cruz, Alejandro; Mateos-Hernandez, Lourdes; Alberdi, Pilar; Villar, Margarita; Riveau, Gilles; Hermann, Emmanuel; Schacht, Anne-Marie; Khalife, Jamal; Correia-Neves, Margarida; Gortazar, Christian; de la Fuente, Jose (Nature Publishing Group, 2017-03-10)
      The identification of factors affecting the susceptibility to infectious diseases is essential toward reducing their burden on the human population. The ABO blood type correlates with susceptibility to malaria and other ...

    • Ixodes scapularis tick cells control Anaplasma phagocytophilum infection by increasing the synthesis of phosphoenolpyruvate from tyrosine 

      Cabezas-Cruz, Alejandro; Espinosa, Pedro J.; Obregon, Dasiel A.; Alberdi, Pilar; de la Fuente, Jose (Frontiers Media, 2017-08-17)
      The obligate intracellular pathogen, Anaplasma phagocytophilum, is the causative agent of life-threatening diseases in humans and animals. A. phagocytophilum is an emerging tick-borne pathogen in the United States, Europe, ...

    • Tick-pathogen interactions and vector competence: Identification of molecular drivers for tick-borne diseases 

      de la Fuente, Jose; Antunes, Sandra; Bonnet, Sarah; Cabezas-Cruz, Alejandro; Domingos, Ana G.; Estrada-Pena, Agustin; Johnson, Nicholas; Kocan, Katherine M.; Mansfield, Karen L.; Nijhof, Ard M.; Papa, Anna; Rudenko, Nataliia; Villar, Margarita; Alberdi, Pilar; Torina, Alessandra; Ayllon, Nieves; Vancova, Marie; Golovchenko, Maryna; Grubhoffer, Libor; Caracappa, Santo; Fooks, Anthony R.; Gortazar, Christian; Rego, Ryan O. M. (Frontiers Media, 2017-04-07)
      Ticks and the pathogens they transmit constitute a growing burden for human and animal health worldwide. Vector competence is a component of vectorial capacity and depends on genetic determinants affecting the ability of ...