Browsing Research Week 2022 by Issue Date
Now showing items 1-20 of 58
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Exploratory analysis of estrogen-mediated gene expression in central ghrelin signaling pathways
(Oklahoma State University Center for Health Sciences, 2022-02-18)Introduction & Objective: As of 2020, 67% of Americans are overweight or obese. Particularly concerning is the greater incidence of obesity in post-menopausal women. Previous studies have shown that estrogen decreases food ... -
Degradation of Beta-Actin in aging blood and semen stains
(Oklahoma State University Center for Health Sciences, 2022-02-18)Piecing together a crime scene is one of the most significant components of any forensic investigation and estimating the age of biological stains at a scene can be crucial to the case. Several studies have demonstrated a ... -
Trauma across generations: a novel look at adverse childhood experiences using the Behavioral Risk Factor Surveillance System
(Oklahoma State University Center for Health Sciences, 2022-02-18)Introduction: The adverse childhood experiences (ACEs) study was one of the first to demonstrate the robust, life-long effects of family dysfunction, child maltreatment, and neglect during childhood. The initial study of ... -
Native American student perspectives on tribally affiliated osteopathic medical school education
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: As the first tribally affiliated medical school, Oklahoma State University College of Osteopathic Medicine at Cherokee Nation (OSUCOM-CN) presents a landmark opportunity for Native American (NA) students. Little ... -
Examining trends in the public’s awareness of exocrine pancreatic insufficiency in the United States using infodemiology metrics
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Exocrine Pancreatic Insufficiency (EPI) is a disorder caused by multiple etiologies leading to decreased pancreatic function. EPI presents with nonspecific symptoms and is largely unknown by the public, making ... -
Fee-waived virtual 5K races allow increase participation compared to in-person races during COVID-19
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Children’s participation in physical exercise has numerous benefits and is well- studied. While there are many significant barriers to participation in exercise in young people, one that has arisen lately is ... -
Sex differences in protein excretion in mice consuming high protein diet
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Normally, the renal excretion of protein (or proteinuria) is absent or very small. Ingesting high-protein diets can elevate proteinuria and in the long term, increase the work on the kidney by increasing ... -
Effects of high salt diet on blood pressure and the renal handling of sodium
(Oklahoma State University Center for Health Sciences, 2022-02-18)Introduction: The association between elevated dietary salt consumption and high blood pressure is well known. Hypertension carries elevated risk for stroke, cardiovascular disease, liver disease, and nervous disorders. ... -
Analysis of gender representation and geographical region of the Communication Disorder Review Committee
(Oklahoma State University Center for Health Sciences, 2022-02-18)Science is at the forefront of diversity, equity, and inclusion yet wide disparities continue to exist in the field today. Science is a field where different backgrounds, experiences, and expertise are critical for progression ... -
Breastfeeding status and its influence on Native American women’s food preferences
(Oklahoma State University Center for Health Sciences, 2022-02-18)Introduction: To evaluate if breastfeeding alters Native American women’s food preferences, recently postpartum women were offered food interest surveys during their 6-week postpartum checkup at W. W. Hastings Indian ... -
Investigation of the microbial and molecular correlates of Morgellons disease
(Oklahoma State University Center for Health Sciences, 2022-02-18)Morgellons disease is a complex dermopathy that is controversial in the medical community. Unfortunately, there is not enough evidence to the etiology or transmission of this disease. Due to the lack of information, the ... -
Clinical trial discontinuation and non-publication for the pharmacologic treatment of Post-Traumatic Stress Disorder among military veterans
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Failures by researchers and clinicians to understand, confront, and overcome barriers in veteran-health research may result in the waste of finite resources. Research waste includes clinical trial discontinuation ... -
Morphine potentiates glucocorticoid receptor translocation in neuronal cells
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: The hypothalamic-pituitary-adrenal (HPA) axis plays a central role in regulating signaling by glucocorticoid receptor which is expressed in almost all cells. Adrenocorticotropin hormone (ACTH) and β-endorphin ... -
Correlation between gluteus medius strength and lower back pain in middle-aged adults: a critically appraised topic
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Low back pain is one of the most common complaints of middle-aged individuals. Low back pain tends to be the result of a more sedentary lifestyle and even for those who are active, normal biomechanics can often ... -
Investigation of acetate sensitivity within shf1 Chlamydomonas mutants
(Oklahoma State University Center for Health Sciences, 2022-02-18)Cilia and flagella are essential for human health. Defects in the assembly and function of these organelles are associated with a collection of disorders called ciliopathies. Studies have suggested that regulation of ciliary ... -
Cultural pathway to osteopathic medical school: The Native American pre-admissions workshop
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Native Americans (NAs) experience significant health disparities compared to the general US population. Medical education has a key role to play in addressing these inequities; however, it is currently falling ... -
Detection of RNA methylation patterns of forensically relevant transcripts in dried bloodstains
(Oklahoma State University Center for Health Sciences, 2022-02-18)RNA degradation kinetics can be used to estimate the age of a biological sample found at a crime scene. RNA sequencing of transcripts from various tissue types shows that degradation occurs faster at the 5’ end than the ... -
Analyzing the phenotypic characteristics of environmental C. difficile isolates
(Oklahoma State University Center for Health Sciences, 2022-02-18)Clostridioides difficile (C. difficile) is an anaerobic, spore-forming bacterium. Antibiotic use, hospitalization, advanced age, a compromised immune system, and previous infection puts individuals at an increased risk for ... -
Effects of gram-negative bacterial outer membrane permeabilization on Serratia marcescens' gene expression
(Oklahoma State University Center for Health Sciences, 2022-02-18)Our laboratory has focused on understanding the effects of outer membrane permeabilizer compound 48/80 on the intrinsic resistance of gram-negative bacteria to hydrophobic antibacterial agents such as the biocide triclosan. ... -
Synthetic cannabinoid, WIN 55212-2, leads to changes of proBDNF/BDNF ratio levels in the periaqueductal gray and blood concentrations in the adolescent rat
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: The hemp plant Cannabis sativa—marijuana and hashish are among the most commonly used illicit substances in adolescents and young adults. The synthetic CB1 agonist WIN 55212-2 (WIN) administration to rats and ...