2026-09-23T23:45:50Zhttps://shareok.org/server/oai/requestoai:shareok.org:11244/3187832019-04-27T21:28:44Zcom_11244_1col_11244_10476
Conway, Tyrrell
Maddox, Scott M.
2019-04-27T21:28:44Z
2019-04-27T21:28:44Z
2011
99221341002042
https://hdl.handle.net/11244/318783
The intestinal ecosystem is comprised of bacteria that are both beneficial and detrimental to human health. The opportunistic pathogens residing within the gastrointestinal tract typically function as commensal members of the human microbiota. However, in certain circumstances these bacteria are able to escape the intestine and cause severe infections throughout the host. This dissertation defines the transcriptional adaptation within macrophages and elucidates the role of transcriptional regulation during pathogenicity in the opportunistic pathogen, Enterococcus faecalis.
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Enterococcus faecalis
Virulence (Microbiology)
Macrophages
Genetic regulation
Transcription factors
Transcriptional Adaptation of Enterococcus faecalis within Macrophages and the Role of PerA in Virulence
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Ph.D.
College of Arts and Sciences::Department of Microbiology and Plant Biology
open.access