Studying the effects of antibiotics on mitochondrial inhibitors
Abstract
The usage of ivermectin (ivm) to treat COVID-19 is controversial. According to a study, ivermectin helped treat COVID-19, but clinical trials showed that ivermectin with the tetracycline-class antibiotic doxycycline overcame the effects of ivermectin to a certain degree2. The goal of this project is to understand why this occurs. Cell cultures were used as a model. Rather than overcoming the effects of ivermectin, tetracycline seems to prevent ivermectin from mitochondrial inhibition. This effect seems to occur when tetracycline is administered first, with ivermectin administered after one hour or more; the effect is prevented when ivermectin is administered, left for two hours, and then tetracycline is added and left for one hour.
Citation
Saleh, M., & Sheaff, R. J. (2021, October 9). Studying the effects of antibiotics on mitochondrial inhibitors. Poster presented at the Oklahoma Louis Stokes Alliance for Minority Participation's 27th Annual Research Symposium, Stillwater, OK.