Show simple item record

dc.contributor.authorKaur, Japneet
dc.contributor.authorFerguson, Steven L.
dc.contributor.authorFreitas, Eduardo
dc.contributor.authorMiller, Ryan
dc.contributor.authorBemben, Debra
dc.contributor.authorKnehans, Allen
dc.contributor.authorBemben, Michael G.
dc.date.accessioned2019-02-05T22:56:12Z
dc.date.available2019-02-05T22:56:12Z
dc.date.issued2019-01-11
dc.identifier.citationKaur, J.; Ferguson, S.L.; Freitas, E.; Miller, R.; Bemben, D.; Knehans, A.; Bemben, M. Association of Vitamin D Status with Chronic Disease Risk Factors and Cognitive Dysfunction in 50–70 Year Old Adults. Nutrients 2019, 11, 141en_US
dc.identifier.urihttps://hdl.handle.net/11244/317118
dc.description.abstractVitamin D deficiency/insufficiency has been primarily associated with skeletal disorders, however, since vitamin D receptors are found on multiple types of cells, there is also a link to increased chronic disease risk and all-cause mortality. The aim of this study was to examine whether deficient/insufficient vitamin D levels are associated with risk factors of chronic diseases and cognitive dysfunction in 50 to 70 year old adults. Participants completed the health status, three-day dietary record and vitamin D food frequency, sun exposure, and international physical activity questionnaires. Cognitive function of the participants was assessed using the Automated Neuropsychological Assessment Metrics while body composition (percent body fat, android/gynoid ratio) was assessed using Dual Energy X-ray Absorptiometry. Applanation tonometry was used to obtain pressure wave forms at the radial artery to examine arterial stiffness and central pressures. A fasting blood draw was taken to measure vitamin D, blood lipid and glucose levels. Fifty percent of the participants (36/72) were vitamin D deficient/insufficient. Individuals in the low physical activity (PA) group had lower serum vitamin D concentration compared to those in the high PA group (p = 0.04). Moreover, serum vitamin D levels were negatively related to risk factors of chronic diseases; blood glucose (r = −0.38; p = 0.01), triglycerides (r = −0.27; p = 0.02), and android/gynoid ratio (r = −0.32; p = 0.01). Deficient/insufficient vitamin D levels are linked to the risk factors of chronic diseases in men and women aged 50 to 70 years.en_US
dc.description.sponsorshipThis research received no external funding. The APC was funded by University of Oklahoma Libraries, and Department of Health and Exercise Science at University of Oklahoma. Publication fees were paid in part by the University of Oklahoma Libraries Open Access Subvention Funden_US
dc.languageen_USen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectphysical activityen_US
dc.subjectelderlyen_US
dc.subject1, 25 dihydroxy vitamin Den_US
dc.subject25 hydroxy vitamin Den_US
dc.titleAssociation of Vitamin D Status with Chronic Disease Risk Factors and Cognitive Dysfunction in 50–70 Year Old Adultsen_US
dc.typeArticleen_US
dc.description.peerreviewYesen_US
dc.identifier.doidoi:10.3390/nu11010141en_US
ou.groupCollege of Arts and Sciences::Department of Health and Exercise Scienceen_US


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record


Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International